Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.34 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.34 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12648428 | 0.83 | NOTUM (0.50) | HPGDSLTA4HHCRTR1HCRTR2CYP3A4 | |
| SCHEMBL1804513 | 0.83 | PRKCI (0.53) | HPGDSLTA4HHCRTR1HCRTR2CYP3A4 | |
| SCHEMBL9454674 | 0.83 | HPGDS (0.46) | HPGDSLTA4HHCRTR1HCRTR2CYP3A4 | |
| SCHEMBL28164766 | 0.83 | HPGDS (0.46) | HPGDSLTA4HHCRTR1HCRTR2CYP3A4 | |
| SCHEMBL9507339 | 0.82 | HPGDS (0.53) | HPGDSLTA4HHCRTR1HCRTR2CYP3A4 | |
| SCHEMBL3964365 | 0.82 | HPGDS (0.58) | HPGDSLTA4HTRPM4NOTUMCHRNA7 | |
| SCHEMBL6221648 | 0.81 | HPGDS (0.44) | HPGDSLTA4HHCRTR1HCRTR2CYP3A4 | |
| SCHEMBL16383003 | 0.80 | HPGDS (0.43) | HPGDSLTA4HHCRTR1HCRTR2CYP3A4 | |
| SCHEMBL14983820 | 0.80 | HPGDS (0.43) | HPGDSLTA4HHCRTR1HCRTR2CYP3A4 | |
| SCHEMBL10366022 | 0.79 | LTA4H (0.50) | HPGDSLTA4HCHRNA7CHRNA10CHRNA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041567-A | Human and veterianary medicine; veneral diseases respiratory diseases, bovine mastitis | BEECHAM GROUP PLC (GB) | 1991-08-20 | — | — | US | disclosed |
| US-4812470-A | Antibacterial monic acid derivatives | BEECHAM GROUP P.L.C. (GB) | 1989-03-14 | — | — | US | disclosed |
| EP-0087953-B1 | ANTIBACTERIAL 1-NORMON-2-YL-HETEROCYCLIC COMPOUNDS | BEECHAM GROUP PLC (GB) | 1988-04-27 | — | — | EP | disclosed |
| EP-0087953-A2 | Antibacterial 1-normon-2-yl-heterocyclic compounds | BEECHAM GROUP PLC (GB) | 1983-09-07 | — | — | EP | disclosed |