Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 10/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.37 |
| ▸ | ESRRA | P11474 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 2/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28169317 | 0.87 | POLQ (0.41) | POLQFFAR4 | |
| SCHEMBL28849269 | 0.85 | TAS2R14 (0.36) | PDE2ASRD5A2 | |
| SCHEMBL28899732 | 0.77 | CES2 (0.41) | POLQCES2ESRRAPDE2ARXRA | |
| SCHEMBL28168829 | 0.72 | GPR52 (0.32) | — | |
| SCHEMBL28849286 | 0.71 | TDP1 (0.33) | — | |
| SCHEMBL28159931 | 0.70 | GPR52 (0.47) | FFAR4 | |
| SCHEMBL28133636 | 0.70 | GRIK1 (0.46) | — | |
| SCHEMBL15094094 | 0.70 | POLQ (0.51) | POLQDAOCES2FFAR4 | |
| SCHEMBL18299914 | 0.69 | CYP1A1 (0.38) | CES2PDE2A | |
| SCHEMBL18299918 | 0.69 | CYP1A1 (0.38) | CES2PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107098846-A | N- acyl sulfonamides class FBPase inhibitor, its preparation method, pharmaceutical composition and purposes | 中国医学科学院药物研究所 | 2017-08-29 | — | — | CN | disclosed |