Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 2/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 2/20 | 0.30 |
| ▸ | THRB | P10828 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28168829 | 0.86 | GPR52 (0.32) | — | |
| SCHEMBL28169406 | 0.85 | POLQ (0.40) | SRD5A2PDE2A | |
| SCHEMBL28169295 | 0.82 | FFAR4 (0.36) | — | |
| SCHEMBL28159931 | 0.79 | GPR52 (0.47) | — | |
| SCHEMBL28849286 | 0.75 | TDP1 (0.33) | MAPT | |
| SCHEMBL28169317 | 0.75 | POLQ (0.41) | — | |
| SCHEMBL23148082 | 0.75 | PDE2A (0.36) | TAS2R14PDE2APTPN1PTPN6PTPN11 | |
| SCHEMBL18586803 | 0.72 | IDO1 (0.38) | TAS2R14PTPN1THRATHRBMAPT | |
| SCHEMBL28847179 | 0.71 | GPR52 (0.43) | — | |
| SCHEMBL3681324 | 0.70 | THRA (0.49) | TAS2R14THRATHRBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107098846-A | N- acyl sulfonamides class FBPase inhibitor, its preparation method, pharmaceutical composition and purposes | 中国医学科学院药物研究所 | 2017-08-29 | — | — | CN | disclosed |