Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.55 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.49 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.42 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.42 |
| ▸ | SCD | O00767 | 1/20 | 0.42 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11436917 | 0.95 | RIPK1 (0.60) | RIPK1HSD11B1PARP14PARP10CHRNB2 | |
| SCHEMBL1651691 | 0.83 | RIPK1 (0.51) | RIPK1HSD11B1PARP14PARP10BACE1 | |
| SCHEMBL938757 | 0.83 | RIPK1 (0.59) | RIPK1HSD11B1PARP14PARP10BACE1 | |
| SCHEMBL30964008 | 0.80 | SPHK2 (0.43) | RIPK1 | |
| SCHEMBL27574946 | 0.79 | RIPK1 (0.62) | RIPK1HSD11B1PARP14PARP10BACE1 | |
| SCHEMBL4019469 | 0.79 | RIPK1 (0.62) | RIPK1HSD11B1PARP14PARP10BACE1 | |
| SCHEMBL216202 | 0.79 | RIPK1 (0.62) | RIPK1HSD11B1PARP14PARP10BACE1 | |
| SCHEMBL27574934 | 0.79 | RIPK1 (0.62) | RIPK1HSD11B1PARP14PARP10BACE1 | |
| SCHEMBL27593250 | 0.79 | RIPK1 (0.54) | RIPK1HSD11B1PARP14PARP10BACE1 | |
| SCHEMBL8957415 | 0.79 | CCNC (0.46) | RIPK1SCD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103547579-B | Fused imidazole derivatives as IDO inhibitors | 新联基因公司 | 2017-02-15 | — | — | CN | claimed |
| CN-107148419-A | The inhibitor of ZESTE enhancers homologue 2 | 葛兰素史密斯克莱知识产权（第2 号）有限公司 | 2017-09-08 | — | — | CN | disclosed |