Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 11/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6153199 | 0.86 | OPRD1 (0.46) | OPRD1PDE2ARIPK1ROCK2 | |
| SCHEMBL28170397 | 0.80 | RIPK1 (0.55) | RIPK1 | |
| SCHEMBL28148131 | 0.78 | TACR1 (0.49) | OPRD1RIPK1ROCK2 | |
| SCHEMBL17142310 | 0.77 | RIPK1 (0.51) | OPRD1RIPK1ROCK2 | |
| SCHEMBL8957415 | 0.76 | CCNC (0.46) | SPHK2SPHK1RIPK1 | |
| SCHEMBL17454889 | 0.75 | RIPK1 (0.50) | RIPK1ROCK2 | |
| SCHEMBL11436917 | 0.75 | RIPK1 (0.60) | RIPK1 | |
| Hydrochloric Acid SCHEMBL16610587 | 0.75 | MAOA (0.46) | SPHK2SPHK1RIPK1ROCK2 | |
| Hydrochloric Acid SCHEMBL16610762 | 0.75 | MAOA (0.46) | SPHK2SPHK1RIPK1ROCK2 | |
| SCHEMBL29236303 | 0.74 | PDE2A (0.41) | OPRD1PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12403139-B2 | Methods and compositions for prevention and treatment of cardiac hypertrophy | UNIVERSITY OF HAWAII (US) | 2025-09-02 | — | — | US | disclosed |
| US-20240189303-A1 | METHODS AND COMPOSITIONS FOR PREVENTION AND TREATMENT OF CARDIAC HYPERTROPHY | UNIVERSITY OF HAWAII | 2024-06-13 | — | — | US | disclosed |