Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28102787 | 0.76 | ALDH1A1 (0.45) | NPBWR1HSP90AA1ALDH1A1KDM4EMAPT | |
| SCHEMBL28170669 | 0.76 | CYP11B1 (0.49) | ALDH1A1KDM4EMAPTCYP19A1GRIN1 | |
| SCHEMBL6116487 | 0.75 | ALDH1A1 (0.65) | NPBWR1ALDH1A1MAPTCMA1TP53 | |
| SCHEMBL22353100 | 0.74 | HSP90AA1 (0.52) | NPBWR1HSP90AA1HSP90AB1ALDH1A1KDM4E | |
| SCHEMBL28434180 | 0.73 | PTGS2 (0.53) | HSP90AA1ALDH1A1CMA1GSK3AGSK3B | |
| SCHEMBL11819451 | 0.72 | MAPT (0.55) | HSP90AA1ALDH1A1KDM4EMAPTALOX15 | |
| SCHEMBL29709490 | 0.71 | CYP19A1 (0.52) | HSP90AA1CMA1TP53GSK3AGSK3B | |
| SCHEMBL10900630 | 0.71 | MEN1 (0.63) | NPBWR1MEN1KMT2A | |
| SCHEMBL22253375 | 0.70 | NOS1 (0.38) | ALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL27976622 | 0.70 | HDAC6 (0.56) | MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074814-A | Glucose transport inhibitor | 拜耳制药股份公司 | 2017-08-18 | — | — | CN | disclosed |