Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrazine SCHEMBL11630131 | 0.97 | LTA4H (0.49) | LTA4HALDH1A1LMNAHPGDMIF | |
| SCHEMBL27601987 | 0.79 | LTA4H (0.47) | LTA4HALDH1A1LMNAHPGDMIF | |
| SCHEMBL13610298 | 0.79 | TP53 (0.40) | LTA4HALDH1A1LMNAHPGDRAB9A | |
| SCHEMBL2129775 | 0.77 | ALDH1A1 (0.52) | ALDH1A1LMNAMIFRAB9ACYP2D6 | |
| SCHEMBL2751117 | 0.77 | L3MBTL1 (0.59) | LTA4HALDH1A1LMNARAB9AMEN1 | |
| SCHEMBL29349000 | 0.77 | ESR1 (0.48) | ALDH1A1MIF | |
| SCHEMBL28258872 | 0.76 | APLNR (0.47) | ALDH1A1LMNAMEN1KMT2ACYP2D6 | |
| SCHEMBL28128728 | 0.76 | LTA4H (0.52) | LTA4HALDH1A1LMNAHPGDMIF | |
| SCHEMBL6131012 | 0.76 | CYP1A2 (0.40) | ALDH1A1CYP11B1CYP11B2CYP2D6SMN1; SMN2 | |
| SCHEMBL3076036 | 0.74 | CYP1A2 (0.47) | ALDH1A1LMNACYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |
| CN-107074805-A | GLS1 inhibitor for treating disease | 德州大学系统董事会 | 2017-08-18 | — | — | CN | disclosed |