Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 5/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2129775 | 0.85 | ALDH1A1 (0.52) | CYP1A2ALDH1A1CYP2D6CTDSP1SMN1; SMN2 | |
| SCHEMBL3076036 | 0.82 | CYP1A2 (0.47) | CYP1A2ALDH1A1HRH3CYP2D6CYP2C9 | |
| SCHEMBL28210941 | 0.80 | CYP1A2 (0.38) | CYP1A2ALDH1A1CYP2D6CTDSP1CHRM1 | |
| SCHEMBL29349000 | 0.80 | ESR1 (0.48) | CYP1A2ALDH1A1CTDSP1L3MBTL1 | |
| SCHEMBL28174339 | 0.76 | LTA4H (0.52) | CYP11B1CYP11B2CYP19A1ALDH1A1CYP2D6 | |
| SCHEMBL5407176 | 0.76 | CYP1A2 (0.43) | CYP1A2ALDH1A1HRH3CYP2D6CYP2C9 | |
| Hydrazine SCHEMBL11630131 | 0.73 | LTA4H (0.49) | CYP11B1CYP11B2ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL29525303 | 0.73 | — | — | |
| SCHEMBL242473 | 0.73 | — | — | |
| SCHEMBL2750124 | 0.72 | L3MBTL1 (0.63) | CYP1A2CYP11B1CYP11B2ALDH1A1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050054647-A1 | New pharmaceutical combination | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2005-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050054647-A1 | New pharmaceutical combination | VEGFA, INHA, PGF | CYP1A2 228/4885CYP11B1 86/4885CYP11B2 33/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.