Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28174676 | 0.81 | TP53 (0.31) | — | |
| SCHEMBL875722 | 0.81 | LTA4H (0.38) | LTA4HPTGS2TSHRSOAT1PCSK9 | |
| SCHEMBL7529688 | 0.79 | LTA4H (0.37) | LTA4HPTGS2TSHRSOAT1PCSK9 | |
| SCHEMBL2655578 | 0.79 | LTA4H (0.37) | LTA4HPTGS2TSHRSOAT1PCSK9 | |
| SCHEMBL7408504 | 0.78 | LTA4H (0.36) | LTA4HPTGS2TSHRSOAT1PCSK9 | |
| SCHEMBL2655575 | 0.78 | LTA4H (0.36) | LTA4HPTGS2TSHRSOAT1PCSK9 | |
| SCHEMBL3481751 | 0.78 | LTA4H (0.36) | LTA4HPTGS2TSHRSOAT1PCSK9 | |
| SCHEMBL3481385 | 0.76 | LTA4H (0.39) | LTA4HPTGS2TSHRSOAT1CYP1A2 | |
| SCHEMBL14078154 | 0.76 | PCSK9 (0.30) | LTA4HPCSK9 | |
| SCHEMBL28039482 | 0.75 | PTGS2 (0.37) | LTA4HPTGS2TSHRSOAT1PCSK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107216349-A | A kind of preparation method of five-membered cyclic disiloxane compound | 杭州师范大学 | 2017-09-29 | — | — | CN | disclosed |