Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 4/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | AKT2 | P31751 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2818475 | 0.87 | BACE1 (0.34) | BACE1NR1H4ALOX5KDM4ERAB9A | |
| SCHEMBL1727420 | 0.80 | NPC1 (0.50) | KDM4ERAB9AHRH3NPC1ALDH1A1 | |
| SCHEMBL2815003 | 0.79 | HRH3 (0.39) | BACE1NR1H4ALOX5KDM4ERAB9A | |
| SCHEMBL1727274 | 0.72 | ALDH1A3 (0.41) | KDM4ERAB9AMAPTHRH3NPC1 | |
| SCHEMBL3628363 | 0.70 | TLR9 (0.49) | KDM4ERAB9ANPC1ALDH1A1PKM | |
| SCHEMBL3682169 | 0.67 | PPARG (0.39) | SMN1; SMN2 | |
| SCHEMBL3686163 | 0.66 | ALDH1A1 (0.44) | KDM4ERAB9AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7630706 | 0.66 | PKM (0.60) | RAB9AMAPTGAAPKM | |
| SCHEMBL34466222 | 0.66 | SMYD2 (0.34) | KDM4EALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL2818377 | 0.65 | L3MBTL1 (0.53) | RAB9AMAPTGAAALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100249418-A1 | NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2010-09-30 | — | — | US | disclosed |
| EP-2213672-A1 | NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID | Nihon Medi-Physics Co., Ltd. (JP) | 2010-08-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249418-A1 | NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID | APP, APBA1, C1QBP | BACE1 4/4885NR1H4 1853/4885ALOX5 3691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.