Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5496809 | 0.87 | MC4R (0.59) | NPC1RAB9ATP53SIGMAR1FAAH | |
| SCHEMBL922710 | 0.87 | PRMT6 (0.57) | ALDH1A1KDM4ETDP1POLBSMN1; SMN2 | |
| SCHEMBL6736373 | 0.85 | SMN1; SMN2 (0.58) | ALDH1A1KDM4ETDP1POLBSMN1; SMN2 | |
| SCHEMBL28855158 | 0.83 | SIGMAR1 (0.57) | TDP1SIGMAR1KMT2AMEN1 | |
| SCHEMBL13490043 | 0.83 | MEN1 (0.60) | ALDH1A1KDM4ETDP1POLBKMT2A | |
| SCHEMBL4367879 | 0.83 | NCF1 (0.60) | ALDH1A1KDM4ENPC1RAB9ATP53 | |
| SCHEMBL374541 | 0.80 | TNNI3K (0.47) | ALDH1A1KDM4ETDP1NPC1RAB9A | |
| SCHEMBL13489987 | 0.80 | ACKR3 (0.45) | ALDH1A1SIGMAR1HSD17B10KMT2AMEN1 | |
| SCHEMBL19986930 | 0.80 | ALDH1A1 (0.65) | ALDH1A1KDM4ENPC1RAB9ATP53 | |
| SCHEMBL12764114 | 0.80 | ALDH1A1 (0.62) | ALDH1A1KDM4ETDP1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107205391-A | Histone demethylase inhibitors | 赛尔基因昆蒂赛尔研究公司 | 2017-09-26 | — | — | CN | disclosed |