Pyridine

Pyridine

SCHEMBL28175673

CC(C)(C)OC(=O)NN1CCNCC1.c1ccncc1

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACACB O00763 1/20 0.36
ACACA Q13085 1/20 0.36
RAB9A P51151 2/20 0.35
LIPE Q05469 1/20 0.34
GNAI3 P08754 1/20 0.34
GNAO1 P09471 1/20 0.34
GNAI1 P63096 1/20 0.34
NAMPT P43490 1/20 0.34
CYP17A1 P05093 2/20 0.33
MAPK1 P28482 1/20 0.33
EPHX2 P34913 1/20 0.33
GPR119 Q8TDV5 1/20 0.32
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
GAA P10253 1/20 0.32
KMT2A Q03164 1/20 0.32
BUB1 O43683 2/20 0.32
P2RY1 P47900 1/20 0.32
KCNA3 P22001 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL853648 0.87 GNAI3 (0.41) ACACBACACALIPEGNAI3GNAO1
SCHEMBL7151133 0.81 GNAI3 (0.38) ACACBACACALIPEGNAI3GNAO1
Pyridine SCHEMBL28276860 0.78 MAPK1 (0.49) MAPK1GPR119
SCHEMBL13398353 0.77 CTSK (0.34) LIPEGNAI3GNAO1GNAI1MEN1
Pyridine SCHEMBL28251823 0.76 GNAI3 (0.36) GNAI3GNAO1GNAI1NAMPTGAA
Pyridine SCHEMBL28281619 0.75 KDM1A (0.46) EPHX2GAAKMT2ABUB1KCNA3
SCHEMBL1926835 0.72 ALDH1A1 (0.45) CYP17A1GPR119GAAALDH1A1
SCHEMBL1576452 0.71 CTSK (0.40) LIPEGAA
SCHEMBL477283 0.71 LIPE (0.42) LIPEGAA
SCHEMBL29179933 0.71 LIPE (0.38) LIPE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105593221-B Compound with somatostatin receptor agonistic activity and pharmaceutical use thereof 小野药品工业株式会社 2017-09-22 CN disclosed