SCHEMBL477283

SCHEMBL477283

CC(C)(C)OC(=O)NN1CCCC1

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LIPE Q05469 3/20 0.42
CTSK P43235 4/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
CTSL P07711 1/20 0.39
CTSB P07858 1/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
HPGD P15428 1/20 0.38
BTK Q06187 1/20 0.38
GAA P10253 1/20 0.37
USP2 O75604 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL694641 0.98 LIPE (0.44) LIPECTSKL3MBTL1CTSLCTSB
SCHEMBL7365934 0.98 LIPE (0.44) LIPECTSKL3MBTL1CTSLCTSB
SCHEMBL1576452 0.96 CTSK (0.40) LIPECTSKL3MBTL1CTSLCTSB
SCHEMBL28702168 0.87 USP2 (0.39) LIPECTSKL3MBTL1CTSLCTSB
SCHEMBL1430236 0.84 LIPE (0.36) LIPECTSKL3MBTL1CTSLCTSB
SCHEMBL7151133 0.84 GNAI3 (0.38) LIPECTSKL3MBTL1CTSLCTSB
SCHEMBL27760998 0.83 EPHX1 (0.38) LIPECTSKL3MBTL1CTSLCTSB
SCHEMBL5651167 0.83 LIPE (0.39) LIPECTSKL3MBTL1CTSLCTSB
SCHEMBL28942305 0.83 EPHX1 (0.41) LIPECTSKL3MBTL1CTSLCTSB
SCHEMBL853648 0.82 GNAI3 (0.41) LIPECTSKCA1CA2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 395 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015104602-A2 A PROCESS FOR THE PREPARATION OF ANAGLIPTIN AND ITS INTERMEDIATES THEREOF WOCKHARDT LIMITED (IN) 2015-07-16 WO claimed
CN-118459425-B Preparation method of pyrrolidine-1-amine-dihydrochloride 南通华祥医药科技有限公司 2025-11-14 CN disclosed
CN-119930589-A Tricyclic compound, pharmaceutical composition and application 广州国家实验室 2025-05-06 CN disclosed
CN-118459425-A Preparation method of pyrrolidine-1-amine-dihydrochloride 南通华祥医药科技有限公司 2024-08-09 CN disclosed
CN-118459425-A Preparation method of pyrrolidine-1-amine-dihydrochloride 南通华祥医药科技有限公司 2024-08-09 CN disclosed
US-11912721-B2 Fused pentacyclic imidazole derivatives UCB Biopharma SRL (BE) 2024-02-27 US disclosed
EP-3740478-B1 FUSED IMIDAZOLE DERIVATIVES AS IL-17 MODULATORS UCB Biopharma SRL (BE) 2023-11-01 EP disclosed
CN-116903628-A FGFR2 inhibitors and methods of use 深圳福沃药业有限公司 2023-10-20 CN disclosed
CN-111601799-B Fused imidazole derivatives as Il-17 modulators UCB生物制药有限责任公司 2023-06-09 CN disclosed
US-11472794-B2 Fused imidazole derivatives as IL-17 modulators UCB Biopharma SRL (BE) 2022-10-18 US disclosed
EP-0757675-A1 NOVEL QUINOLONE 5-(N-HETEROSUBSTITUTED AMINO) ANTIMICROBIALS THE PROCTER & GAMBLE COMPANY (US) 1997-02-12 EP disclosed
US-5599816-A BACTERICIDE ABBOTT LABORATORIES (US) 1997-02-04 US disclosed
WO-1996039407-A1 QUINOLIZINONE TYPE COMPOUNDS ABBOTT LABORATORIES (US) 1996-12-12 WO disclosed
WO-1996039384-A1 SUBSTITUTED N-(INDOLE-2-CARBONYL)-GLYCINAMIDES AND DERIVATIVES AS GLYCOGEN PHOSPHORYLASE INHIBITORS PFIZER, INC. (US) 1996-12-12 WO disclosed
CN-1137273-A Quinolizinone type compounds ABBOTT LAB (US) 1996-12-04 CN disclosed
WO-1995029894-A1 NOVEL QUINOLONE 5-(N-HETEROSUBSTITUTED AMINO) ANTIMICROBIALS THE PROCTER & GAMBLE COMPANY (US) 1995-11-09 WO disclosed
EP-0666853-A1 ANTIMICROBIAL 5-HYDRAZINO-QUINOLONE DERIVATIVES THE PROCTER & GAMBLE COMPANY (US) 1995-08-16 EP disclosed
WO-1994010163-A1 ANTIMICROBIAL 5-HYDRAZINO-QUINOLONE DERIVATIVES THE PROCTER & GAMBLE COMPANY (US) 1994-05-11 WO disclosed
EP-0341493-A2 Optically active pyridonecarboxylic acid derivatives DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1989-11-15 EP disclosed
EP-0310854-A1 Process for the manufacture of 3-amino-1-benzyl-pyrrolidines BAYER AG (DE) 1989-04-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11472794-B2 Fused imidazole derivatives as IL-17 modulators IL17A, IL2, IL23R LIPE 4425/4885CTSK 992/4885L3MBTL1 3057/4885
US-11912721-B2 Fused pentacyclic imidazole derivatives TNF, NFKBIA, TNFRSF1A LIPE 4425/4885CTSK 2690/4885L3MBTL1 3573/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.