Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LPL | P06858 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL28176643 | 0.88 | SMN1; SMN2 (0.59) | SMN1; SMN2CYP2C19SRCPLK1ALDH1A1 | |
| Phosphoric Acid SCHEMBL28050913 | 0.79 | ENPP2 (0.56) | SMN1; SMN2PLK1ALDH1A1EGFRCA2 | |
| Phosphoric Acid SCHEMBL27438207 | 0.77 | ABAT (0.46) | CA2TAAR1 | |
| Phosphoric Acid SCHEMBL28710500 | 0.77 | ENPP2 (0.67) | ALDH1A1LPLLIPGEGFRTP53 | |
| Ethylbenzene SCHEMBL31175848 | 0.76 | TP53 (0.70) | SMN1; SMN2CYP2C19SRCALDH1A1HPGD | |
| Ethylbenzene SCHEMBL7043912 | 0.76 | TP53 (0.70) | SMN1; SMN2CYP2C19SRCALDH1A1HPGD | |
| Ethylbenzene SCHEMBL27296172 | 0.76 | TP53 (0.70) | SMN1; SMN2CYP2C19SRCALDH1A1HPGD | |
| SCHEMBL968796 | 0.74 | LMNA (0.56) | SMN1; SMN2CYP2C19SRCPLK1ALDH1A1 | |
| SCHEMBL11304410 | 0.74 | ENPP2 (0.60) | SMN1; SMN2CYP2C19SRCPLK1ALDH1A1 | |
| SCHEMBL344618 | 0.74 | SMN1; SMN2 (0.52) | SMN1; SMN2CYP2C19SRCPLK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101842434-A | Polypropylene composition, method of making the same, and articles made therefrom | DOW GLOBAL TECHNOLOGIES INC | 2010-09-22 | — | — | CN | disclosed |
| CN-100516120-C | Olefin block copolymers, production processes of same and use thereof | MITSUI CHEMICALS INC (JP) | 2009-07-22 | — | — | CN | disclosed |
| CN-100453566-C | Ethylene (co) polymers and use thereof | MITSUI CHEMICALS INC (JP) | 2009-01-21 | — | — | CN | disclosed |
| CN-100436492-C | Olefin polymer | MITSUI CHEMICALS INC (JP) | 2008-11-26 | — | — | CN | disclosed |
| CN-100357330-C | Polar group-containing olefin copolymer, thermoplastic resin composition containing the copolymer, and uses thereof | MITSUI CHEMICALS INC (JP) | 2007-12-26 | — | — | CN | disclosed |
| CN-100335509-C | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof | MITSUI CHEMICALS INC (JP) | 2007-09-05 | — | — | CN | disclosed |
| CN-1326892-C | Ethylene copolymer and ethylene/alpha-olefin copolymer composition and propylene polymer composition both containing the ethylene copolymer | MITSUI CHEMICALS INC (JP) | 2007-07-18 | — | — | CN | disclosed |
| CN-1303120-C | Adhesive resin and adhesive resin composition for liquid crystalline polymer | MITSUI CHEMICALS INC (JP) | 2007-03-07 | — | — | CN | disclosed |
| CN-1763114-A | Ethylene copolymer and ethylene/alpha-olefin copolymer composition and propylene polymer composition both containing the ethylene copolymer | MITSUI CHEMICALS INC (JP) | 2006-04-26 | — | — | CN | disclosed |
| CN-1737016-A | Polar group-containing olefin copolymer, thermoplastic resin composition containing the copolymer, and uses thereof | MITSUI CHEMICALS INC (JP) | 2006-02-22 | — | — | CN | disclosed |
| CN-1362972-A | Olefin polymer and process for producing the same | MITSUI CHEMICALS INC (JP) | 2002-08-07 | — | — | CN | disclosed |
| CN-1344752-A | Modified polyolefine and resin composition containing the same | MITSUI CHEMICALS INC (JP) | 2002-04-17 | — | — | CN | disclosed |
| CN-1342715-A | Polar group-containing olefin copolymer, process for producing the same, thermoplastic resin composition containing the same, and use thereof | MITSUI CHEMICALS INC (JP) | 2002-04-03 | — | — | CN | disclosed |
| CN-1314921-A | Ethylene (co) polymers and their use | MITSUI CHEMICALS INC (JP) | 2001-09-26 | — | — | CN | disclosed |
| CN-1313880-A | Soft syndiotactic polypropylene compositions and shaped products | MITSUI CHEMICALS INC (JP) | 2001-09-19 | — | — | CN | disclosed |
| CN-1300787-A | Propylene ethylene block copolymer, resin composition and blown plastic articles | IDEMITSU PETROCHEMICAL CO (JP) | 2001-06-27 | — | — | CN | disclosed |
| CN-1226906-A | Triblock oligomers, thermoplastic resin compositions, and antifog moldings | MITSUI CHEMICALS INC (JP) | 1999-08-25 | — | — | CN | disclosed |
| CN-1219177-A | Olefin polymerization catalyst and olefin polymerization process, and olefin polymer composition and hot molded product | MITSUI CHEMICALS INC (JP) | 1999-06-09 | — | — | CN | disclosed |
| CN-1212003-A | Ethylene copolymer composition and moldings | MITSUI CHEMICALS INC (JP) | 1999-03-24 | — | — | CN | disclosed |
| CN-1209827-A | 'alpha'-olefin/aromatic vinyl copolymer composition and products thereof | MITSUI CHEMICALS INC (JP) | 1999-03-03 | — | — | CN | disclosed |