Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 11/20 | 0.40 |
| ▸ | CTSS | P25774 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 2/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2178104 | 0.87 | CTSK (0.46) | CTSKCTSSATMACECTSB | |
| SCHEMBL2177717 | 0.84 | CTSK (0.45) | CTSKCTSSATMACECTSB | |
| SCHEMBL2818140 | 0.78 | L3MBTL1 (0.50) | CTSKCTSS | |
| SCHEMBL2821039 | 0.77 | GPR88 (0.39) | CTSKCTSSCA2 | |
| SCHEMBL22042132 | 0.76 | CTSK (0.62) | CTSKCTSSATMACECTSB | |
| SCHEMBL28108976 | 0.76 | CTSK (0.62) | CTSKCTSSATMACECTSB | |
| SCHEMBL27730329 | 0.76 | CTSK (0.62) | CTSKCTSSATMACECTSB | |
| SCHEMBL2157516 | 0.75 | MEN1 (0.36) | CTSKCA2 | |
| SCHEMBL2754724 | 0.74 | CTSK (0.55) | CTSKCTSSCA2ATMACE | |
| SCHEMBL2179437 | 0.71 | ITGB1 (0.40) | CTSKCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010048332-A2 | COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | ACUCELA, INC. (US) | 2010-04-29 | — | — | WO | disclosed |