SCHEMBL28181550

SCHEMBL28181550

NC(N)(c1ccccc1)c1ccccc1.NNC(=O)N(N)CC1CCCCC1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.40
KEAP1 Q14145 1/20 0.39
NFE2L2 Q16236 1/20 0.39
CHRM2 P08172 6/20 0.39
CHRM1 P11229 6/20 0.39
CHRM3 P20309 6/20 0.39
CCR1 P32246 2/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
EPHX1 P07099 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
MEN1 O00255 1/20 0.36
ALDH1A1 P00352 1/20 0.36
KMT2A Q03164 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
KIF11 P52732 1/20 0.36
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27843733 0.83 ALOX5 (0.48) EPHX1ALDH1A1KMT2A
SCHEMBL5300153 0.73 HDAC1 (0.53) EPHX2HDAC1HDAC6EPHX1KMT2A
SCHEMBL5305672 0.71 HDAC1 (0.51) EPHX2HDAC1HDAC6KMT2A
SCHEMBL28181551 0.68 CYP2C9 (0.41) KEAP1NFE2L2CHRM2CHRM1CHRM3
SCHEMBL27894311 0.67 TAAR1 (0.43) HDAC1HDAC6ALDH1A1KMT2AKIF11
SCHEMBL10396129 0.66 ALOX5 (0.44) EPHX2HDAC1HDAC6EPHX1KMT2A
SCHEMBL1850878 0.66 KEAP1 (0.66) KEAP1NFE2L2CHRM2CHRM1CHRM3
SCHEMBL1850881 0.66 KEAP1 (0.66) KEAP1NFE2L2CHRM2CHRM1CHRM3
SCHEMBL4429615 0.66 ALOX5 (0.52) HDAC1HDAC6EPHX1KMT2A
Cyclopropane SCHEMBL28218385 0.65 KCNN4 (0.58) CHRM2CHRM1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104995021-B Aqueous resin coating laminated metal plate 株式会社神户制钢所 2017-11-14 CN disclosed