Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | AGER | Q15109 | 3/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | OXTR | P30559 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5305672 | 0.98 | HDAC1 (0.51) | HDAC1HDAC6EPHX2SMN1; SMN2ALOX5 | |
| SCHEMBL8389321 | 0.86 | PDK1 (0.48) | HDAC1HDAC6ALOX5KMT2AOPRM1 | |
| SCHEMBL7761513 | 0.79 | HSD11B1 (0.54) | HDAC1HDAC6EPHX2AGERMTNR1A | |
| SCHEMBL8199326 | 0.76 | HDAC1 (0.58) | HDAC1HDAC6EPHX2SMN1; SMN2KMT2A | |
| SCHEMBL16924162 | 0.76 | TRPM8 (0.52) | HDAC1HDAC6 | |
| SCHEMBL29172999 | 0.75 | HDAC1 (0.57) | HDAC1HDAC6OXTROPRM1OPRD1 | |
| SCHEMBL3954244 | 0.75 | AGER (0.48) | SMN1; SMN2AGERMTNR1AKMT2A | |
| SCHEMBL25890659 | 0.74 | HDAC1 (0.50) | HDAC1HDAC6AGERMTNR1AOPRM1 | |
| SCHEMBL28181550 | 0.73 | EPHX2 (0.40) | HDAC1HDAC6EPHX2KMT2AEPHX1 | |
| SCHEMBL4429615 | 0.73 | ALOX5 (0.52) | HDAC1HDAC6ALOX5KMT2AEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025776-A2 | CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-03-08 | — | — | WO | disclosed |