Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NAAA | Q02083 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ITGAV | P06756 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | CTSG | P08311 | 1/20 | 0.46 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28472074 | 0.89 | NAAA (0.59) | NPC1RAB9ASMN1; SMN2NAAAGAA | |
| SCHEMBL27993602 | 0.88 | NAAA (0.61) | NPC1RAB9ASMN1; SMN2NAAAGAA | |
| SCHEMBL10872706 | 0.87 | RAB9A (0.56) | NPC1RAB9ASMN1; SMN2NAAAGAA | |
| SCHEMBL28856753 | 0.86 | EPHX2 (0.59) | NPC1RAB9ASMN1; SMN2NAAAGAA | |
| SCHEMBL13885360 | 0.84 | ALDH1A1 (0.57) | NPC1RAB9ASMN1; SMN2GAAEPHX2 | |
| SCHEMBL20214202 | 0.82 | ACACB (0.48) | SMN1; SMN2GAAKMT2AHSD17B10LMNA | |
| SCHEMBL23911908 | 0.82 | RAB9A (0.54) | NPC1RAB9ASMN1; SMN2NAAAGAA | |
| SCHEMBL1769658 | 0.81 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2GAAEPHX2 | |
| SCHEMBL12471405 | 0.81 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2NAAAGAA | |
| SCHEMBL16613793 | 0.81 | RAB9A (0.53) | NPC1RAB9ASMN1; SMN2NAAAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107325019-B | Aryl amine benzamide compound and N- aryl-aryl amine benzamide compound preparation method | 石河子大学 | 2019-11-22 | — | — | CN | disclosed |
| CN-107325019-A | The preparation method of aryl amine benzamide compound and N aryl aryl amine benzamide compounds | 石河子大学 | 2017-11-07 | — | — | CN | disclosed |