Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | SHBG | P04278 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27451487 | 0.83 | MAOA (0.41) | MAOAMAOBCISD1ACHECYP2C9 | |
| SCHEMBL27720997 | 0.80 | ESR1 (0.53) | GAAESR1ESR2OPRK1 | |
| SCHEMBL11790878 | 0.79 | MAOA (0.45) | MAOAMAOBCISD1ACHECYP2C9 | |
| SCHEMBL17748780 | 0.78 | NPC1 (0.40) | PTPN1DAO | |
| SCHEMBL9441932 | 0.78 | PTPN1 (0.46) | PTPN1DAO | |
| SCHEMBL16191256 | 0.77 | KCNH2 (0.42) | OPRK1DAO | |
| SCHEMBL10356888 | 0.77 | CYP1A2 (0.42) | CYP2C9CYP2C19CYP2D6CYP1A2BCL2 | |
| SCHEMBL11675641 | 0.75 | ACHE (0.42) | ACHEPTPN1OPRK1 | |
| SCHEMBL17281697 | 0.75 | ACHE (0.36) | MAOAMAOBCISD1ACHECYP2C9 | |
| SCHEMBL17748785 | 0.74 | CEL (0.41) | OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101326215-A | Poly (arylene ether) copolymer | GEN ELECTRIC (US) | 2008-12-17 | — | — | CN | claimed |
| CN-101305030-A | Polyfunctional poly(arylene ether) method | GEN ELECTRIC (US) | 2008-11-12 | — | — | CN | claimed |
| CN-105452318-B | Rigid foam and correlated product | 沙特基础全球技术有限公司 | 2017-11-28 | — | — | CN | disclosed |
| CN-105531323-A | Composition and article comprising thermoplastic polyurethane and particulate engineering polymer | SABIC INNOVATIVE PLASTICS IP BV | 2016-04-27 | — | — | CN | disclosed |
| CN-105473656-A | Poly(phenylene ether) /epoxy homogeneous solid and powder coating composition incorporating same | SABIC INNOVATIVE PLASTICS IP BV | 2016-04-06 | — | — | CN | disclosed |
| CN-105452318-A | Rigid foam and associated article | SABIC INNOVATIVE PLASTICS IP BV | 2016-03-30 | — | — | CN | disclosed |
| CN-101326215-A | Poly (arylene ether) copolymer | GEN ELECTRIC (US) | 2008-12-17 | — | — | CN | disclosed |