Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.53 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.42 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16191256 | 0.84 | KCNH2 (0.42) | OPRK1NPC1RAB9ALTA4H | |
| SCHEMBL1291889 | 0.82 | ERCC1 (0.54) | ERCC1ERCC4GAABACE1 | |
| SCHEMBL17748785 | 0.81 | CEL (0.41) | OPRK1NPC1THRATHRBRAB9A | |
| SCHEMBL30921631 | 0.81 | CEL (0.41) | OPRK1NPC1THRATHRBRAB9A | |
| SCHEMBL28182371 | 0.80 | MAOA (0.42) | ESR1ESR2OPRK1GAA | |
| SCHEMBL22990868 | 0.79 | SLC6A2 (0.47) | LTA4H | |
| SCHEMBL13086023 | 0.79 | NUDT1 (0.43) | ERCC1ERCC4OPRK1GAAPKM | |
| SCHEMBL12239177 | 0.79 | CA2 (0.46) | ERCC1ERCC4NPC1GAANUDT1 | |
| SCHEMBL5191935 | 0.79 | ERCC1 (0.40) | ERCC1ERCC4NUDT1BACE1TDP1 | |
| SCHEMBL28717773 | 0.77 | OPRK1 (0.36) | OPRK1NPC1GAAPKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101305030-B | Polyfunctional poly(arylene ether) method | GEN ELECTRIC | 2011-07-13 | — | — | CN | claimed |
| CN-101326215-A | Poly (arylene ether) copolymer | GEN ELECTRIC (US) | 2008-12-17 | — | — | CN | claimed |
| CN-101305030-A | Polyfunctional poly(arylene ether) method | GEN ELECTRIC (US) | 2008-11-12 | — | — | CN | claimed |
| CN-105283482-B | Thermoplastic polyurethanes and related methods and articles | 沙特基础全球技术有限公司 | 2017-12-08 | — | — | CN | disclosed |
| CN-105452318-B | Rigid foam and correlated product | 沙特基础全球技术有限公司 | 2017-11-28 | — | — | CN | disclosed |
| CN-105531323-A | Composition and article comprising thermoplastic polyurethane and particulate engineering polymer | SABIC INNOVATIVE PLASTICS IP BV | 2016-04-27 | — | — | CN | disclosed |
| CN-105473656-A | Poly(phenylene ether) /epoxy homogeneous solid and powder coating composition incorporating same | SABIC INNOVATIVE PLASTICS IP BV | 2016-04-06 | — | — | CN | disclosed |
| CN-105452318-A | Rigid foam and associated article | SABIC INNOVATIVE PLASTICS IP BV | 2016-03-30 | — | — | CN | disclosed |
| CN-105283482-A | Thermoplastic polyurethanes and related methods and articles | SABIC GLOBAL TECHNOLOGIES BV | 2016-01-27 | — | — | CN | disclosed |
| CN-102762633-B | Methods for the preparation of a poly(arylene ether) polysiloxane multiblock copolymer | SABIC INNOVATIVE PLASTICS IP | 2014-06-25 | — | — | CN | disclosed |
| CN-102762633-A | Methods for the preparation of a poly(arylene ether) polysiloxane multiblock copolymer | SABIC INNOVATIVE PLASTICS IP | 2012-10-31 | — | — | CN | disclosed |
| CN-101326215-B | Poly (arylene ether) copolymer | SABIC INNOVATIVE PLASTICS IP | 2012-05-23 | — | — | CN | disclosed |
| CN-101305030-B | Polyfunctional poly(arylene ether) method | GEN ELECTRIC | 2011-07-13 | — | — | CN | disclosed |
| CN-101326215-A | Poly (arylene ether) copolymer | GEN ELECTRIC (US) | 2008-12-17 | — | — | CN | disclosed |
| CN-101305030-A | Polyfunctional poly(arylene ether) method | GEN ELECTRIC (US) | 2008-11-12 | — | — | CN | disclosed |