Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR2E1 | Q9Y466 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.43 |
| ▸ | RB1 | P06400 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR5A | P47898 | 1/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8582769 | 0.80 | SIGMAR1 (0.47) | NR2E1SIGMAR1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL14473893 | 0.80 | BRD3 (0.58) | NR2E1SIGMAR1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL28912217 | 0.80 | NR2E1 (0.50) | NR2E1SIGMAR1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8822945 | 0.76 | RB1 (0.45) | SIGMAR1KDM4EALDH1A1SMN1; SMN2DRD2 | |
| SCHEMBL8595169 | 0.75 | SIRT1 (0.50) | NR2E1SIGMAR1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL3258128 | 0.74 | SIRT1 (0.63) | NR2E1SIGMAR1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1877922 | 0.73 | BRD3 (0.67) | NR2E1BRD3RB1 | |
| SCHEMBL8822941 | 0.73 | SMN1; SMN2 (0.46) | SIGMAR1KDM4EALDH1A1SMN1; SMN2DRD2 | |
| SCHEMBL24727249 | 0.72 | SIGMAR1 (0.49) | NR2E1SIGMAR1KDM4EDRD2DRD1 | |
| SCHEMBL11848642 | 0.71 | KDM4E (0.50) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107235891-B | Preparation method of 4-bromocarbazole | 北京八亿时空液晶科技股份有限公司 | 2020-02-21 | — | — | CN | claimed |
| CN-107235891-A | A kind of preparation method of 4 bromine carbazole | 北京八亿时空液晶科技股份有限公司 | 2017-10-10 | — | — | CN | claimed |
| CN-107235891-B | Preparation method of 4-bromocarbazole | 北京八亿时空液晶科技股份有限公司 | 2020-02-21 | — | — | CN | disclosed |
| CN-107235891-B | Preparation method of 4-bromocarbazole | 北京八亿时空液晶科技股份有限公司 | 2020-02-21 | — | — | CN | disclosed |
| CN-107235891-A | A kind of preparation method of 4 bromine carbazole | 北京八亿时空液晶科技股份有限公司 | 2017-10-10 | — | — | CN | disclosed |