Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | HTR5A | P47898 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dihydrophenanthridine SCHEMBL2087461 | 0.88 | CA12 (0.56) | CA12CA9ALOX15HSD17B10JAK2 | |
| Dihydrophenanthridine SCHEMBL29791568 | 0.88 | CA12 (0.56) | CA12CA9ALOX15HSD17B10JAK2 | |
| SCHEMBL27425414 | 0.86 | CA12 (0.54) | CA12CA9ALOX15HSD17B10JAK2 | |
| SCHEMBL11474110 | 0.77 | CA12 (0.59) | CA12CA9ALOX15HSD17B10JAK2 | |
| SCHEMBL21665091 | 0.77 | CA12 (0.48) | CA12CA9ALOX15HSD17B10JAK2 | |
| Fluorene SCHEMBL28263838 | 0.75 | MAOA (0.61) | MAOAKDM4ENPC1ALDH1A1LMNA | |
| SCHEMBL19594919 | 0.75 | PARP1 (0.49) | CA12CA9ALOX15HSD17B10JAK2 | |
| SCHEMBL21602736 | 0.73 | ALOX15 (0.53) | CA12CA9ALOX15HSD17B10JAK2 | |
| SCHEMBL14581370 | 0.71 | CA12 (0.68) | CA12CA9ALOX15HSD17B10MAOA | |
| SCHEMBL3692772 | 0.71 | NOS2 (0.41) | CA12CA9ALOX15HSD17B10JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107474041-A | 5‑（The carbonyl of benzofuran 2) 6 formamide 5,6 dihydrophenanthridine derivative and synthesis and application | 西安石油大学 | 2017-12-15 | — | — | CN | disclosed |
| CN-107474041-A | 5‑（The carbonyl of benzofuran 2) 6 formamide 5,6 dihydrophenanthridine derivative and synthesis and application | 西安石油大学 | 2017-12-15 | — | — | CN | disclosed |