Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GSTK1 | Q9Y2Q3 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | PPARD | Q03181 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7162252 | 0.86 | FFAR4 (0.44) | FFAR4FFAR1LMNAALDH1A1GSTK1 | |
| SCHEMBL11727672 | 0.85 | FFAR4 (0.47) | FFAR4FFAR1LMNAALDH1A1GSTK1 | |
| SCHEMBL29138962 | 0.85 | FFAR4 (0.47) | FFAR4FFAR1LMNAALDH1A1GSTK1 | |
| SCHEMBL27998378 | 0.85 | FFAR4 (0.47) | FFAR4FFAR1LMNAALDH1A1GSTK1 | |
| SCHEMBL27613424 | 0.82 | LMNA (0.48) | FFAR4FFAR1LMNAALDH1A1GSTK1 | |
| SCHEMBL8645646 | 0.80 | TSHR (0.41) | FFAR4FFAR1LMNAALDH1A1GSTK1 | |
| SCHEMBL9540341 | 0.80 | GABRP (0.40) | FFAR4FFAR1LMNAALDH1A1GSTK1 | |
| SCHEMBL22190520 | 0.79 | ALDH1A1 (0.43) | FFAR4FFAR1LMNAALDH1A1GSTK1 | |
| SCHEMBL2346153 | 0.78 | GPR84 (0.46) | FFAR4FFAR1PPARDGPR84 | |
| SCHEMBL28130977 | 0.76 | LMNA (0.46) | FFAR4FFAR1LMNAALDH1A1GSTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104230865-B | 4 amino butyric acid derivatives of biaryl substituted and its production and use | 上海翰森生物医药科技有限公司 | 2018-01-09 | — | — | CN | disclosed |
| CN-105143183-B | 4 amino butyric acid derivatives of biaryl substituted and its production and use | 上海翰森生物医药科技有限公司 | 2018-01-09 | — | — | CN | disclosed |