SCHEMBL28197

SCHEMBL28197

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nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.33
LMNA P02545 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27561548 1.00 AKR1B1 (0.33) AKR1B1LMNAL3MBTL1TDP1
SCHEMBL98729 1.00 AKR1B1 (0.33) AKR1B1LMNAL3MBTL1TDP1
Water SCHEMBL28186002 0.98 AKR1B1 (0.32) AKR1B1LMNAL3MBTL1
SCHEMBL28599341 0.89
SCHEMBL25264497 0.87 LMNA (0.40) AKR1B1LMNAL3MBTL1TDP1
SCHEMBL671071 0.87 LMNA (0.40) AKR1B1LMNAL3MBTL1TDP1
SCHEMBL28985161 0.87 LMNA (0.40) AKR1B1LMNAL3MBTL1TDP1
SCHEMBL6795503 0.87 LMNA (0.40) AKR1B1LMNAL3MBTL1TDP1
SCHEMBL599601 0.87 LMNA (0.40) AKR1B1LMNAL3MBTL1TDP1
SCHEMBL16513133 0.80 AKR1B1 (0.32) AKR1B1LMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6676 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4393511-A1 LIPID COMPOUND AND USE THEREOF Themedium Therapeutics Co., Ltd. (CN) 2024-07-03 EP claimed
EP-4393484-A1 COMPOSITION FOR ORGAN-SPECIFIC DELIVERY OF NUCLEIC ACID Themedium Therapeutics Co., Ltd. (CN) 2024-07-03 EP claimed
US-11976279-B2 Methods and compositions for managing vascular conditions using miR-483 mimics and HIF1alpha pathway inhibitors EMORY UNIVERSITY (US) 2024-05-07 US claimed
US-11851656-B2 Chemically modified single-stranded RNA-editing oligonucleotides PROQR THERAPEUTICS II B.V. (NL) 2023-12-26 US claimed
CN-116744942-A MICRORNA-29 compounds, compositions and therapeutic uses thereof 高士威治疗有限公司 2023-09-12 CN claimed
EP-4232580-A2 MICRORNA-29 COMPOUNDS, COMPOSITIONS AND USES IN THERAPY Causeway Therapeutics Limited (GB) 2023-08-30 EP claimed
CN-116410978-A Small interfering nucleic acid, preparation and application thereof 佑嘉(杭州)生物医药科技有限公司 2023-07-11 CN claimed
CN-110352244-B Chemically modified RNA editing single stranded oligonucleotides ProQR治疗上市公司Ⅱ 2023-03-21 CN claimed
US-20230039928-A1 Antisense oligonucleotides for nucleotide deamination in the treatment of Stargardt disease PROQR THERAPEUTICS II B.V. (NL) 2023-02-09 US claimed
CN-113186203-B Vaccine agent for treating or preventing coronavirus diseases 斯微(上海)生物科技股份有限公司 2022-12-30 CN claimed
US-20070072796-A1 methylation modulators; phosphoramidite building blocks; for treating cancer and hematological disorders ASTEX PHARMACEUTICALS, INC. 2007-03-29 US claimed
US-20060292603-A1 Method for selecting a chemical entity from a tagged library NUEVOLUTION A/S (DK) 2006-12-28 US claimed
US-20060286581-A1 Heteroconfigurational Polynucleotides and Methods of Use APPLERA CORPORATION; APPLIED BIOSYSTEMS GROUP (US) 2006-12-21 US claimed
EP-1465913-A1 HETEROCONFIGURATIONAL POLYNUCLEOTIDE AND METHODS OF USE Applera Corporation (US) 2004-10-13 EP claimed
US-20030198980-A1 Comprising a D-form polynucleotide sequence portion and an L-form polynucleotide sequence portion that are covalently linked APPLERA CORPORATION 2003-10-23 US claimed
WO-2003059929-A1 HETEROCONFIGURATIONAL POLYNUCLEOTIDE AND METHODS OF USE APPLERA CORPORATION (US) 2003-07-24 WO claimed
CN-1113892-C Process for preparation of 2'-fluoro-5-methyl-beta-L-arabino-furanosyluridine UNIV OF GEORGIA RES FOUNDATION (US) 2003-07-09 CN claimed
US-6548298-B2 Transcriptional unit complementary to human telomerase RNA sequence linked to regulating sequences GERON CORPORATION 2003-04-15 US claimed
US-6512107-B2 Generating preferential uridine derivative THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION 2003-01-28 US claimed
US-5958680-A NUCLEIC ACIDS COMPRISING THE RNA COMPONENT OF A MAMMALIAN TELOMERASE ARE USEFUL AS PHARMACEUTICAL, THERAPEUTIC, AND DIAGNOSTIC REAGENTS. GERON CORPORATION (US) 1999-09-28 US claimed