SCHEMBL671071

SCHEMBL671071

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nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
PDE4A P27815 1/20 0.34
USP2 O75604 1/20 0.32
SLCO1B1 Q9Y6L6 1/20 0.32
AKR1B1 P15121 1/20 0.31
KDM4E B2RXH2 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL599601 1.00 LMNA (0.40) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL6795503 1.00 LMNA (0.40) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL25264497 1.00 LMNA (0.40) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL28985161 1.00 LMNA (0.40) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL98729 0.87 AKR1B1 (0.33) LMNAL3MBTL1TDP1AKR1B1
SCHEMBL28197 0.87 AKR1B1 (0.33) LMNAL3MBTL1TDP1AKR1B1
SCHEMBL27561548 0.87 AKR1B1 (0.33) LMNAL3MBTL1TDP1AKR1B1
Water SCHEMBL28186002 0.85 AKR1B1 (0.32) LMNAL3MBTL1AKR1B1
SCHEMBL968310 0.81 LMNA (0.42) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL457880 0.81 LMNA (0.42) LMNAL3MBTL1TDP1PDE4AUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250017950-A1 COMPOUNDS FOR TREATING MITOCHONDRIAL DNA DISORDERS UCL BUSINESS LTD (GB) 2025-01-16 US claimed
EP-4433077-A1 COMPOUNDS FOR TREATING MITOCHONDRIAL DNA DISORDERS UCL Business Ltd (GB) 2024-09-25 EP claimed
CN-114453428-B Method for preventing rear-end collision of strip steel in finish rolling and coiling 首钢京唐钢铁联合有限责任公司 2024-05-10 CN claimed
CN-116411353-A Synthesis method of DNA coding compound oxo-glycoside 成都先导药物开发股份有限公司 2023-07-11 CN claimed
WO-2023089313-A1 COMPOUNDS FOR TREATING MITOCHONDRIAL DNA DISORDERS UCL BUSINESS LTD (GB) 2023-05-25 WO claimed
US-20130184330-A1 COMPOSITIONS AND METHODS FOR INDUCING CANCER CELL DEATH UNIVERSITY OF MIAMI (US) 2013-07-18 US claimed
WO-2012024234-A1 COMPOSITIONS AND METHODS FOR INDUCING CANCER CELL DEATH UNIVERSITY OF MIAMI (US) 2012-02-23 WO claimed
US-20260009062-A1 TRANSFER OF C2'-EPIMERIZED SUGARS TO THE AMPHOTERICIN B AGLYCONE UNIV ILLINOIS (US) 2026-01-08 US disclosed
CN-119730733-A Kit for promoting developmental myelination 雀巢产品有限公司 2025-03-28 CN disclosed
US-12216326-B2 Optical member driving mechanism TDK TAIWAN CORP. (TW) 2025-02-04 US disclosed
US-20250017950-A1 COMPOUNDS FOR TREATING MITOCHONDRIAL DNA DISORDERS UCL BUSINESS LTD (GB) 2025-01-16 US disclosed
EP-4433077-A1 COMPOUNDS FOR TREATING MITOCHONDRIAL DNA DISORDERS UCL Business Ltd (GB) 2024-09-25 EP disclosed
CN-118256607-A ACGH gene chip and kit for detecting fetal birth defects caused by chromosome microdeletion and microduplication and application thereof 中山康源基因技术科技有限公司 2024-06-28 CN disclosed
EP-1986660-A2 HEXOSE COMPOUNDS TO TREAT CANCER Board of Regents, The University of Texas System (US) 2008-11-05 EP disclosed
WO-2007101148-A2 HEXOSE COMPOUNDS TO TREAT CANCER BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2007-09-07 WO disclosed
WO-2007100728-A2 MANNOSE DERIVATIVES FOR KILLING TUMOR CELLS UNIVERSITY OF MIAMI (US) 2007-09-07 WO disclosed
CN-1771043-A Treatment of cancer with 2-deoxyglucose THRESHOLD PHARMACEUTICALS INC (US) 2006-05-10 CN disclosed
US-5994502-A CONTACTING A PEPTIDE CONTAINING ASPARAGINE IN A GLYCOSYLATION RECOGNITION MOTIF WITH A COMPOUND OF GLUCOSE-MANNOSE-N-ACETYLGLUCOSAMINE-PYROPHOSPHATE-DOLICHOL AND THE ENZYME, ISOLATING FORMED GLYCOPEPTIDE NATIONAL INSTITUTES OF HEALTH 1999-11-30 US disclosed
US-5721338-A BIOSYNTHESIS OF GLYCOPEPTIDES CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1998-02-24 US disclosed
WO-1991009971-A1 CHROMOGENIC 5-POSITION MODIFIED NEURAMINIC ACID SUBSTRATES AND METHODS FOR DIAGNOSING HUMAN INFLUENZA THEREWITH SYMEX CORP. (US) 1991-07-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260009062-A1 TRANSFER OF C2'-EPIMERIZED SUGARS TO THE AMPHOTERICIN B AGLYCONE ERG28, SLC2A9, GALE LMNA 1600/4885L3MBTL1 394/4885TDP1 4536/4885
US-20250017950-A1 COMPOUNDS FOR TREATING MITOCHONDRIAL DNA DISORDERS POLRMT, TK2, GOT2 LMNA 2348/4885L3MBTL1 518/4885TDP1 115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.