Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL599601 | 1.00 | LMNA (0.40) | LMNAL3MBTL1TDP1PDE4AUSP2 | |
| SCHEMBL25264497 | 1.00 | LMNA (0.40) | LMNAL3MBTL1TDP1PDE4AUSP2 | |
| SCHEMBL28985161 | 1.00 | LMNA (0.40) | LMNAL3MBTL1TDP1PDE4AUSP2 | |
| SCHEMBL671071 | 1.00 | LMNA (0.40) | LMNAL3MBTL1TDP1PDE4AUSP2 | |
| SCHEMBL98729 | 0.87 | AKR1B1 (0.33) | LMNAL3MBTL1TDP1AKR1B1 | |
| SCHEMBL28197 | 0.87 | AKR1B1 (0.33) | LMNAL3MBTL1TDP1AKR1B1 | |
| SCHEMBL27561548 | 0.87 | AKR1B1 (0.33) | LMNAL3MBTL1TDP1AKR1B1 | |
| Water SCHEMBL28186002 | 0.85 | AKR1B1 (0.32) | LMNAL3MBTL1AKR1B1 | |
| SCHEMBL968310 | 0.81 | LMNA (0.42) | LMNAL3MBTL1TDP1PDE4AUSP2 | |
| SCHEMBL457880 | 0.81 | LMNA (0.42) | LMNAL3MBTL1TDP1PDE4AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040096951-A1 | Crystal structures of retaining glycosytransferases | BRITISH COLUMBIA, UNIVERSITY OF , THE (CA) | 2004-05-20 | — | — | US | disclosed |
| US-5770407-A | Process for preparing nucleotide inhibitors of glycosyltransferases | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-06-23 | — | — | US | disclosed |
| WO-1998025940-A1 | INHIBITORS OF GLYCOSYLTRANSFERASES | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-06-18 | — | — | WO | disclosed |