Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27561548 | 1.00 | AKR1B1 (0.33) | AKR1B1LMNAL3MBTL1TDP1 | |
| SCHEMBL28197 | 1.00 | AKR1B1 (0.33) | AKR1B1LMNAL3MBTL1TDP1 | |
| Water SCHEMBL28186002 | 0.98 | AKR1B1 (0.32) | AKR1B1LMNAL3MBTL1 | |
| SCHEMBL28599341 | 0.89 | — | — | |
| SCHEMBL25264497 | 0.87 | LMNA (0.40) | AKR1B1LMNAL3MBTL1TDP1 | |
| SCHEMBL671071 | 0.87 | LMNA (0.40) | AKR1B1LMNAL3MBTL1TDP1 | |
| SCHEMBL28985161 | 0.87 | LMNA (0.40) | AKR1B1LMNAL3MBTL1TDP1 | |
| SCHEMBL6795503 | 0.87 | LMNA (0.40) | AKR1B1LMNAL3MBTL1TDP1 | |
| SCHEMBL599601 | 0.87 | LMNA (0.40) | AKR1B1LMNAL3MBTL1TDP1 | |
| SCHEMBL16513133 | 0.80 | AKR1B1 (0.32) | AKR1B1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 6682 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4108770-A1 | AGE-SELEX METHOD FOR APTAMER IDENTIFICATION AND USE | Aptamimetics GmbH (DE) | 2022-12-28 | — | — | EP | claimed |
| CN-114729355-A | PPM1A inhibitors and methods of using the same | 奎里斯公司 | 2022-07-08 | — | — | CN | claimed |
| CN-113924492-A | Detection of microbial endotoxins in oral samples using aptamers | 宝洁公司 | 2022-01-11 | — | — | CN | claimed |
| CN-113631709-A | Compositions and methods for treating KCNT 1-related disorders | 普拉克西斯精密药物股份有限公司 | 2021-11-09 | — | — | CN | claimed |
| US-11008570-B2 | 3′ end caps for RNAi agents for use in RNA interference | NOVARTIS AG (CH) | 2021-05-18 | — | — | US | claimed |
| CN-112654705-A | micro-RNA inhibitors for use in the treatment of metabolic diseases | 德国亥姆霍兹慕尼黑中心健康与环境研究中心（有限公司） | 2021-04-13 | — | — | CN | claimed |
| CN-105792832-B | Organic compounds for the treatment of hepatitis B virus | 诺华股份有限公司 | 2021-03-23 | — | — | CN | claimed |
| CN-109295187-B | Dislocation sequencing method for directly sequencing non-natural nucleic acid based on nanopore | 南京大学 | 2021-02-09 | — | — | CN | claimed |
| EP-3722277-A2 | 3'END CAPS FOR RNA-INTERFERRING AGENTS FOR USE IN RNA | Novartis AG (CH) | 2020-10-14 | — | — | EP | claimed |
| CN-111050745-A | Nucleic acid ligands for consumer product compositions | 宝洁公司 | 2020-04-21 | — | — | CN | claimed |
| WO-2015153510-A1 | MODIFIED CYTOSINE POLYNUCLEOTIDE OLIGOMERS AND METHODS | CEPHEID (US) | 2015-10-08 | — | — | WO | claimed |
| WO-2015153496-A1 | MODIFIED THYMINE POLYNUCLEOTIDE OLIGOMERS AND METHODS | CEPHEID (US) | 2015-10-08 | — | — | WO | claimed |
| US-20150275278-A1 | MODIFIED THYMINE POLYNUCLEOTIDE OLIGOMERS AND METHODS | CEPHEID (US) | 2015-10-01 | — | — | US | claimed |
| US-20150275283-A1 | MODIFIED CYTOSINE POLYNUCLEOTIDE OLIGOMERS AND METHODS | CEPHEID (US) | 2015-10-01 | — | — | US | claimed |
| US-8895719-B2 | Markers for pre-cancer and cancer cells and the method to interfere with cell proliferation therein | ANDES BIOTECHNOLOGIES S.A. (CL) | 2014-11-25 | — | — | US | claimed |
| US-20130149371-A1 | MARKERS FOR PRE-CANCER AND CANCER CELLS AND THE METHOD TO INTERFERE WITH CELL PROLIFERATION THEREIN | ANDES BIOTECHNOLIGIES S.A. (CL) | 2013-06-13 | — | — | US | claimed |
| US-20090227489-A1 | STAT3 Agonists and Antagonists and Therapeutic Uses Thereof | JOHNS HOPKINS UNIVERSITY (US) | 2009-09-10 | — | — | US | claimed |
| US-6780642-B2 | DETECTING CANCER IN A TISSUE SAMPLE; OBTAIN TISSUE SAMPLE, SCREEN FOR PREFERENTIAL MARKER, PRESENCE OF MARKER INDICATES CANCER | FLORIDA ATLANTIC UNIVERSITY | 2004-08-24 | — | — | US | claimed |
| EP-1308511-A1 | Use of angiopoietin-like 1 and angiopoietin-like 2 nucleic acids and proteins for the treatment of blood-related disorders and defects in vasculature. | Mermaid Pharmaceuticals GmbH (DE) | 2003-05-07 | — | — | EP | claimed |
| WO-1998042723-A9 | METHODS AND COMPOSITIONS FOR THE DIAGNOSIS AND TREATMENT OF NEUROPSYCHIATRIC DISORDERS | — | 1999-03-04 | — | — | WO | claimed |