Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 7/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.35 |
| ▸ | PGR | P06401 | 3/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7495753 | 0.73 | AHR (0.49) | NR3C1PGRNR3C2DHFRIDO1 | |
| SCHEMBL6993553 | 0.72 | PTGS2 (0.50) | PTGS1PTGS2 | |
| SCHEMBL6990951 | 0.67 | DAO (0.49) | NR3C1PGRNR3C2IDO1 | |
| SCHEMBL30076020 | 0.66 | KDM4E (0.43) | EPHX2PPARGNR3C1PGRNR3C2 | |
| SCHEMBL19360302 | 0.66 | KDM4E (0.43) | EPHX2PPARGNR3C1PGRNR3C2 | |
| SCHEMBL6993972 | 0.65 | DAO (0.44) | NR3C1PGRNR3C2IDO1 | |
| SCHEMBL12560322 | 0.64 | PTGDR2 (0.45) | RORC | |
| SCHEMBL8417818 | 0.64 | IDO1 (0.59) | EPHX2PPARGIDO1 | |
| SCHEMBL6994150 | 0.62 | DAO (0.44) | NR3C1PGRNR3C2PTGS1PTGS2 | |
| SCHEMBL14378240 | 0.62 | IDO1 (0.50) | EPHX2PPARGIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107531679-A | Aromatic amides analog derivative, its preparation method and its application in medicine | 江苏恒瑞医药股份有限公司 | 2018-01-02 | — | — | CN | disclosed |