Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6627245 | 0.83 | MTNR1B (0.41) | SLC7A5MTNR1BS1PR1SMN1; SMN2PDK1 | |
| SCHEMBL18055477 | 0.82 | BRD4 (0.49) | SLC7A5MTNR1BPDK1PDK2PDK3 | |
| SCHEMBL2822819 | 0.81 | MTNR1B (0.40) | SLC7A5MTNR1BS1PR1SMN1; SMN2PDK1 | |
| SCHEMBL3063250 | 0.81 | ADRB2 (0.37) | SLC7A5ALDH1A1LMNATP53SMN1; SMN2 | |
| SCHEMBL4497170 | 0.80 | MTNR1B (0.39) | MTNR1BS1PR1ALDH1A1PDK1PDK2 | |
| SCHEMBL2798823 | 0.77 | MTNR1B (0.40) | MTNR1BS1PR1TP53PDK1PDK2 | |
| SCHEMBL4335630 | 0.77 | SLC7A5 (0.39) | SLC7A5ALDH1A1SMN1; SMN2L3MBTL1ITGB1 | |
| SCHEMBL4335628 | 0.77 | SLC7A5 (0.39) | SLC7A5ALDH1A1SMN1; SMN2L3MBTL1ITGB1 | |
| SCHEMBL16141841 | 0.75 | L3MBTL1 (0.38) | MTNR1BPDK1PDK2PDK3PDK4 | |
| SCHEMBL8286492 | 0.75 | ALDH1A1 (0.41) | MTNR1BS1PR1ALDH1A1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2242759-A1 | COMPOUNDS | AstraZeneca AB (SE) | 2010-10-27 | — | — | EP | disclosed |
| WO-2009098448-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2009-08-13 | — | — | WO | disclosed |