Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | DUT | P33316 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ICMT | O60725 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8241203 | 0.83 | ALDH1A1 (0.58) | ALDH1A1KDM4ENPC1MAPTRAB9A | |
| SCHEMBL2814624 | 0.78 | ALDH1A1 (0.61) | ALDH1A1KDM4ENPC1MAPTRAB9A | |
| SCHEMBL30647201 | 0.77 | POLB (0.59) | ALDH1A1NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL5823744 | 0.77 | POLB (0.59) | ALDH1A1NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL8238735 | 0.76 | ALDH1A1 (0.66) | ALDH1A1KDM4ENPC1MAPTRAB9A | |
| SCHEMBL2263898 | 0.74 | DUT (0.52) | ALDH1A1NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL8247540 | 0.73 | ALDH1A1 (0.55) | ALDH1A1KDM4ENPC1MAPTRAB9A | |
| SCHEMBL1093920 | 0.73 | ALDH1A1 (0.65) | ALDH1A1KDM4EARSMN1; SMN2LMNA | |
| SCHEMBL7734845 | 0.73 | HTR1D (0.41) | ALDH1A1KDM4ENPC1RAB9ALMNA | |
| SCHEMBL15792998 | 0.72 | DUT (0.41) | ALDH1A1KDM4EARDUTACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100249123-A1 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | ADDEX PHARMA SA (CH) | 2010-09-30 | — | — | US | disclosed |
| EP-2134676-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | Addex Pharma SA (CH) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008117175-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | ADDEX PHARMA SA (CH) | 2008-10-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249123-A1 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | FSHR, GNRHR, SHBG | ALDH1A1 1769/4885KDM4E 1395/4885NPC1 3400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.