Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.33 |
| ▸ | ALOX15B | O15296 | 2/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.32 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 1/20 | 0.31 |
| ▸ | RARG | P13631 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12433393 | 0.80 | ALOX15B (0.43) | ESR1ESR2TTRALOX15ALOX12 | |
| SCHEMBL24429184 | 0.79 | CHRNB4 (0.38) | ESR1ESR2TTRALOX15ALOX12 | |
| SCHEMBL8354476 | 0.79 | ACHE (0.41) | ESR1ESR2TTR | |
| SCHEMBL19194418 | 0.79 | ESR1 (0.61) | ESR1ESR2TTRALOX15ALOX12 | |
| SCHEMBL25082619 | 0.79 | ACHE (0.41) | ESR1ESR2TTR | |
| SCHEMBL25233691 | 0.79 | ADRA2A (0.41) | ESR1ESR2TTRALOX15ALOX12 | |
| SCHEMBL24090453 | 0.76 | ALOX15 (0.47) | ALOX15ALOX12MTNR1A | |
| SCHEMBL13291827 | 0.76 | TP53 (0.39) | ESR1ESR2TTRLTB4RLTB4R2 | |
| SCHEMBL31525729 | 0.76 | ALOX15 (0.47) | ALOX15ALOX12MTNR1A | |
| SCHEMBL18283983 | 0.73 | RARA (0.55) | ESR1ESR2TTRLTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107709315-A | The inhibitor of bruton's tyrosine kinase | 药品循环有限责任公司 | 2018-02-16 | — | — | CN | disclosed |