Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 2/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10848456 | 0.86 | ANPEP (0.48) | SMN1; SMN2L3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL13495167 | 0.79 | MMP8 (0.50) | SMN1; SMN2L3MBTL1MEN1KMT2AMMP8 | |
| SCHEMBL12997993 | 0.78 | MEN1 (0.51) | SMN1; SMN2L3MBTL1MEN1KMT2AGAA | |
| SCHEMBL5330174 | 0.78 | TSHR (0.50) | SMN1; SMN2L3MBTL1MEN1KMT2AMMP8 | |
| SCHEMBL3690028 | 0.76 | MMP8 (0.48) | SMN1; SMN2L3MBTL1MEN1KMT2AGAA | |
| SCHEMBL16049191 | 0.76 | MMP8 (0.55) | SMN1; SMN2L3MBTL1MEN1KMT2AGAA | |
| SCHEMBL11546992 | 0.76 | PAM (0.46) | SMN1; SMN2L3MBTL1MEN1KMT2AGAA | |
| SCHEMBL7391243 | 0.75 | L3MBTL1 (0.56) | SMN1; SMN2L3MBTL1MEN1KMT2AGAA | |
| SCHEMBL1287178 | 0.75 | TSHR (0.47) | SMN1; SMN2L3MBTL1MEN1KMT2AMMP8 | |
| Hydrochloric Acid SCHEMBL11328850 | 0.75 | PIN1 (0.49) | SMN1; SMN2L3MBTL1MEN1KMT2AMMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107573260-A | A kind of preparation method of α cyano group β carbonyl propionic acid ester type compounds | 浙江工业大学 | 2018-01-12 | — | — | CN | disclosed |