Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4403555 | 0.83 | CA1 (0.56) | MEN1KMT2AATMLMNAALDH1A1 | |
| SCHEMBL4412154 | 0.80 | LMNA (0.56) | MEN1KMT2ALMNAHTR1AALDH1A1 | |
| SCHEMBL6698451 | 0.78 | MAPT (0.59) | MEN1KMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL2661540 | 0.78 | ADRA2C (0.54) | MEN1KMT2AATMLMNAHTR1A | |
| SCHEMBL4172010 | 0.76 | MAPT (0.68) | MEN1KMT2AATMHTR1AALDH1A1 | |
| SCHEMBL25556709 | 0.75 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1TSHRSCN9A | |
| SCHEMBL3436302 | 0.75 | TSHR (0.66) | MEN1KMT2ALMNAALDH1A1TSHR | |
| SCHEMBL3436303 | 0.75 | HTT (0.53) | MEN1KMT2ALMNAHTR1AALDH1A1 | |
| SCHEMBL10963122 | 0.75 | ME2 (0.58) | MEN1KMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL20888096 | 0.74 | ALDH1A1 (0.48) | KMT2AALDH1A1TSHRKDM4EHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107735397-A | GPR55 receptor active selective modulators：Chromene pyrazole derivatives | 高等科学研究委员会（CSIC） | 2018-02-23 | — | — | CN | disclosed |