Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | PLAU | P00749 | 1/20 | 0.51 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6530016 | 0.86 | PLAU (0.50) | ADRA2AADRA2BADRA2CPLAUPLAUR | |
| SCHEMBL28201246 | 0.81 | L3MBTL1 (0.52) | LMNAALDH1A1MEN1KMT2ATAAR1 | |
| SCHEMBL4925039 | 0.78 | MAPT (0.50) | ADRA2AADRA2BADRA2CMAPTNPSR1 | |
| SCHEMBL28201210 | 0.76 | TSHR (0.58) | LMNAPKMALDH1A1MEN1TSHR | |
| SCHEMBL27730027 | 0.76 | RAD52 (0.49) | ADRA2AADRA2BADRA2CMAPTNPSR1 | |
| SCHEMBL29954675 | 0.75 | USP2 (0.45) | ADRA2AADRA2BADRA2CMAPTNPSR1 | |
| SCHEMBL6973198 | 0.75 | ADRA2A (0.65) | ADRA2AADRA2BADRA2CMAPTNPSR1 | |
| SCHEMBL17198006 | 0.73 | ADRA2A (0.58) | ADRA2AADRA2BADRA2CMAPTPKM | |
| SCHEMBL7424307 | 0.72 | ADRA2A (0.57) | ADRA2AADRA2BADRA2CNPSR1PKM | |
| SCHEMBL844603 | 0.72 | PLAU (0.40) | PLAUPLAURLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107735397-A | GPR55 receptor active selective modulators：Chromene pyrazole derivatives | 高等科学研究委员会（CSIC） | 2018-02-23 | — | — | CN | disclosed |