Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7027296 | 0.86 | POLB (0.56) | TSHRPOLBALDH1A1LMNADRD2 | |
| SCHEMBL6936789 | 0.83 | ALDH1A1 (0.58) | TSHRPOLBALDH1A1LMNADRD2 | |
| SCHEMBL8492185 | 0.78 | DRD2 (0.52) | TSHRPOLBALDH1A1LMNADRD2 | |
| Hydrochloric Acid SCHEMBL9994404 | 0.77 | ALDH1A1 (0.58) | POLBALDH1A1LMNADRD2DRD3 | |
| SCHEMBL11081882 | 0.77 | PKM (0.60) | TSHRALDH1A1LMNADRD2DRD3 | |
| SCHEMBL8521489 | 0.77 | ALDH1A1 (0.55) | TSHRPOLBALDH1A1LMNADRD2 | |
| SCHEMBL28201240 | 0.76 | ADRA2A (0.53) | TSHRALDH1A1LMNAPKMAKR1C3 | |
| SCHEMBL8362372 | 0.76 | TSHR (0.68) | TSHRPOLBALDH1A1LMNADRD2 | |
| SCHEMBL30747784 | 0.76 | TSHR (0.68) | TSHRPOLBALDH1A1LMNADRD2 | |
| SCHEMBL8522516 | 0.76 | ALDH1A1 (0.60) | TSHRPOLBALDH1A1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107735397-A | GPR55 receptor active selective modulators：Chromene pyrazole derivatives | 高等科学研究委员会（CSIC） | 2018-02-23 | — | — | CN | disclosed |