SCHEMBL8601625

SCHEMBL8601625

c1ccc(COC23CCCC2O3)cc1

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 4/20 0.39
OPRD1 P41143 2/20 0.39
OPRK1 P41145 2/20 0.39
NR5A2 O00482 1/20 0.37
OPRL1 P41146 3/20 0.36
DPP4 P27487 1/20 0.36
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2128532 0.95 OPRM1 (0.36) OPRM1OPRD1OPRK1OPRL1DPP4
SCHEMBL5743860 0.95 OPRM1 (0.36) OPRM1OPRD1OPRK1OPRL1DPP4
SCHEMBL21504377 0.73 SCN1A (0.40) OPRM1NR5A2OPRL1DPP4TSHR
SCHEMBL28201268 0.70 TSHR (0.39) OPRM1OPRD1OPRK1NR5A2OPRL1
SCHEMBL28200687 0.69 NR5A2 (0.36) OPRM1OPRD1OPRK1NR5A2OPRL1
SCHEMBL30092850 0.68 MAOA (0.41)
SCHEMBL2502222 0.68 NR5A2 (0.37) OPRM1OPRD1OPRK1NR5A2OPRL1
SCHEMBL21753776 0.67 LMNA (0.42) TSHR
SCHEMBL15465574 0.67 CTSV (0.36) OPRM1OPRD1OPRK1NR5A2OPRL1
SCHEMBL15465575 0.67 CTSV (0.36) OPRM1OPRD1OPRK1NR5A2OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4504724-A1 SPLEEN TYROSINE KINASE INHIBITORS Uniquest Pty Limited (AU) 2025-02-12 EP disclosed
WO-2023193054-A1 SPLEEN TYROSINE KINASE INHIBITORS UNIQUEST PTY LTD (AU) 2023-10-12 WO disclosed
US-5750805-A Rearrangement of epoxides THE UNIVERSITY OF READING (GB) 1998-05-12 US disclosed
EP-0750600-A1 REARRANGEMENT OF EPOXIDES THE UNIVERSITY OF READING (GB) 1997-01-02 EP disclosed
WO-1995025079-A1 REARRANGEMENT OF EPOXIDES THE UNIVERSITY OF READING (GB) 1995-09-21 WO disclosed