Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.37 |
| ▸ | FPR2 | P25090 | 5/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP7 | P09237 | 1/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
| ▸ | F2RL1 | P55085 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4060533 | 0.84 | TBXAS1 (0.39) | KDM4EALDH1A1ADRA2AADRA2BADRA2C | |
| SCHEMBL9315687 | 0.82 | CPB2 (0.42) | KDM4EALDH1A1ADRA2AADRA2BADRA2C | |
| Bromide SCHEMBL28351579 | 0.82 | FPR2 (0.43) | KDM4EALDH1A1ADRA2AADRA2BADRA2C | |
| SCHEMBL31547895 | 0.81 | TBXAS1 (0.44) | KDM4EALDH1A1ADRA2AADRA2BADRA2C | |
| SCHEMBL18112879 | 0.81 | FPR2 (0.46) | KDM4EADRA2AADRA2BADRA2CFPR2 | |
| Hydrochloric Acid SCHEMBL28364020 | 0.80 | TBXAS1 (0.45) | KDM4EALDH1A1ADRA2AADRA2BADRA2C | |
| Bromide SCHEMBL28435732 | 0.80 | ADRA2A (0.41) | KDM4EALDH1A1ADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL28363999 | 0.80 | ADRA2A (0.41) | KDM4EALDH1A1ADRA2AADRA2BADRA2C | |
| Bromide SCHEMBL28360500 | 0.80 | TBXAS1 (0.43) | KDM4EALDH1A1ADRA2AADRA2BADRA2C | |
| SCHEMBL9052552 | 0.76 | TAAR1 (0.41) | ADRA2AADRA2BADRA2CCSNK1A1TYRO3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107636009-A | Hyperglycemic factor derivative with improved stability | 韩美药品株式会社 | 2018-01-26 | — | — | CN | claimed |
| CN-107636009-A | Hyperglycemic factor derivative with improved stability | 韩美药品株式会社 | 2018-01-26 | — | — | CN | disclosed |