Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 6/20 | 0.33 |
| ▸ | NPC1 | O15118 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28201505 | 0.81 | PPARG (0.43) | HIF1AMAPTLCKGSK3BBACE1 | |
| SCHEMBL6394555 | 0.72 | ALDH1A1 (0.46) | HIF1ACYP1A1CYP1A2CYP19A1LCK | |
| SCHEMBL28202092 | 0.71 | MAOA (0.47) | HIF1AMAPTMAOAMAOBRAB9A | |
| SCHEMBL28202090 | 0.70 | NPC1 (0.43) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL26011755 | 0.70 | NPC1 (0.38) | HIF1AMAPTCYP1A1CYP1A2CYP19A1 | |
| SCHEMBL2516876 | 0.70 | APP (0.58) | HIF1AMAPTCYP1A2LCKMAOA | |
| SCHEMBL18959614 | 0.69 | RXRA (0.45) | HIF1AMAPTCYP1A1CYP1A2CYP19A1 | |
| SCHEMBL6388039 | 0.68 | APP (0.54) | LCKMAOBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL13242652 | 0.68 | APP (0.54) | LCKMAOBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14749976 | 0.67 | MAOB (0.42) | HIF1AMAPTCYP1A2MAOBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107602478-A | A kind of novel benzimidazoles ion monomer and preparation method thereof | 浙江大学 | 2018-01-19 | — | — | CN | disclosed |