Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.47 |
| ▸ | MAOB | P27338 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13377762 | 0.82 | NPC1 (0.58) | MAOAMAOBRAB9ANPC1TDP1 | |
| SCHEMBL515204 | 0.81 | NPC1 (0.56) | MAOAMAOBRAB9ANPC1TDP1 | |
| SCHEMBL6394555 | 0.81 | ALDH1A1 (0.46) | MAOAMAOBRAB9ANPC1MEN1 | |
| SCHEMBL26011755 | 0.78 | NPC1 (0.38) | MAOAMAOBRAB9ANPC1TDP1 | |
| SCHEMBL8621941 | 0.78 | RAB9A (0.59) | MAOAMAOBRAB9ANPC1TDP1 | |
| SCHEMBL9469211 | 0.78 | RAB9A (0.59) | MAOAMAOBRAB9ANPC1TDP1 | |
| SCHEMBL2854281 | 0.77 | ERN1 (0.42) | MAOAMAOBRAB9ANPC1TDP1 | |
| SCHEMBL18959614 | 0.76 | RXRA (0.45) | MAOAMAOBRAB9ANPC1TDP1 | |
| SCHEMBL13968251 | 0.76 | HMGB1 (0.44) | MAOAMAOBRAB9ANPC1MAPT | |
| SCHEMBL6388039 | 0.75 | APP (0.54) | MAOBRAB9ANPC1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107602478-A | A kind of novel benzimidazoles ion monomer and preparation method thereof | 浙江大学 | 2018-01-19 | — | — | CN | disclosed |