Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL14917 | 0.82 | CA1 (0.38) | TSHRALDH1A1PKMCA12CA1 | |
| Bicarbonate SCHEMBL6150295 | 0.82 | CA1 (0.38) | TSHRALDH1A1PKMCA12CA1 | |
| Oxalic Acid SCHEMBL9728851 | 0.79 | CA12 (0.37) | ALDH1A1PKMCA12CA1CA9 | |
| SCHEMBL785147 | 0.79 | — | — | |
| SCHEMBL338264 | 0.79 | KDM4E (0.34) | ALDH1A1CA12CA1CA9 | |
| SCHEMBL1123 | 0.79 | — | — | |
| SCHEMBL1906466 | 0.77 | MEN1 (0.34) | CYP2C19ALDH1A1PKMCA12CA1 | |
| Acetic Acid SCHEMBL482738 | 0.77 | FFAR3 (0.39) | ALDH1A1PKMCA12CA1CA9 | |
| Carbamic Acid SCHEMBL699756 | 0.77 | ACHE (0.39) | TSHRALDH1A1PKMCA12CA1 | |
| SCHEMBL6742810 | 0.77 | CA12 (0.35) | ALDH1A1PKMCA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107667133-A | Vesicles formed from block copolymer, and novel block copolymer | 应用仿生学有限公司 | 2018-02-06 | — | — | CN | disclosed |