Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHKA | P35790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28026653 | 0.81 | — | — | |
| SCHEMBL28821971 | 0.72 | HCAR3 (0.35) | LOXL2 | |
| SCHEMBL8190030 | 0.72 | LOXL2 (0.31) | LOXL2HCAR2 | |
| SCHEMBL14519358 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL28184282 | 0.70 | CHRM5 (0.50) | LOXL2HCAR2CHRM5CHKA | |
| SCHEMBL8048746 | 0.69 | NOS2 (0.36) | — | |
| SCHEMBL27531641 | 0.68 | — | — | |
| SCHEMBL2103936 | 0.68 | LOXL2 (0.34) | LOXL2CHRM5CHKA | |
| SCHEMBL31555143 | 0.66 | TSHR (0.46) | — | |
| SCHEMBL6098360 | 0.65 | POLB (0.44) | LOXL2HCAR2CHRM5CHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107592859-A | Process for preparing 4-aminopyridazines | 巴斯夫欧洲公司 | 2018-01-16 | — | — | CN | disclosed |