SCHEMBL8190030

SCHEMBL8190030

CCN([C]=O)c1ccnnc1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 1/20 0.31
HCAR2 Q8TDS4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6696457 0.79 CHRM5 (0.43)
SCHEMBL5511544 0.76 HTT (0.45)
SCHEMBL28202065 0.72 LOXL2 (0.35) LOXL2HCAR2
SCHEMBL8191339 0.71 KCNA5 (0.36)
SCHEMBL305841 0.70 TSHR (0.47)
SCHEMBL2807180 0.68 TSHR (0.41)
SCHEMBL4480480 0.67 ESR1 (0.46)
SCHEMBL28821971 0.67 HCAR3 (0.35) LOXL2
SCHEMBL14121955 0.67 ALDH1A1 (0.37)
SCHEMBL8175933 0.67 KCNH2 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6140338-A FOR TREATING ACUTE INFLAMMATORY DISEASES, CHRONIC INFLAMMATORY DISEASES, ACQUIRED IMMUNE DEFICIENCY SYNDROME, CANCER, ISCHEMIC REFLOW DISORDER AND/OR ARTERIOSCLEROSIS BANYU PHARMACEUTICAL, CO., LTD. (JP) 2000-10-31 US disclosed
EP-0916668-A1 CHEMOKINE RECEPTOR ANTAGONISTS BANYU PHARMACEUTICAL CO., LTD. (JP) 1999-05-19 EP disclosed