Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20037648 | 0.75 | NOS2 (0.38) | NOS2GAAMAPTSMN1; SMN2 | |
| SCHEMBL28821971 | 0.74 | HCAR3 (0.35) | MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL11317311 | 0.73 | TSHR (0.52) | MEN1GAAMAPTHTTKMT2A | |
| SCHEMBL22876953 | 0.72 | NOS2 (0.33) | NOS2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21414323 | 0.72 | AOC3 (0.44) | NOS2SMN1; SMN2 | |
| SCHEMBL12663094 | 0.72 | CNR2 (0.43) | NOS2MEN1GAAMAPTHTT | |
| SCHEMBL15926171 | 0.71 | NOS2 (0.35) | NOS2 | |
| SCHEMBL18404001 | 0.70 | ALDH1A1 (0.64) | NOS2MEN1GAAMAPTHTT | |
| SCHEMBL28202065 | 0.69 | LOXL2 (0.35) | — | |
| SCHEMBL19798273 | 0.68 | ALDH1A1 (0.67) | MEN1GAAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009050242-A2 | HETEROCYCLE-SUBSTITUTED PIPERAZINO-DIHYDROTHIENOPYRIMIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-23 | — | — | WO | disclosed |