Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 8/20 | 0.50 |
| ▸ | MAOB | P27338 | 8/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28205855 | 0.78 | MEN1 (0.60) | MEN1KMT2AHSP90AA1MAOAMAOB | |
| SCHEMBL28205908 | 0.73 | NPSR1 (0.74) | NPSR1POLBMEN1KMT2AMAOA | |
| SCHEMBL7039863 | 0.69 | MEN1 (0.61) | NPSR1POLBMEN1KMT2AHSP90AA1 | |
| SCHEMBL10016510 | 0.69 | POLB (1.00) | NPSR1POLBMEN1KMT2AMAOA | |
| SCHEMBL14138529 | 0.68 | PKM (0.66) | PKM | |
| SCHEMBL27955203 | 0.67 | EGFR (0.71) | MEN1KMT2AHSP90AA1TLR9MAOA | |
| SCHEMBL27955195 | 0.67 | EGFR (0.71) | MEN1KMT2AHSP90AA1TLR9CA1 | |
| SCHEMBL27955191 | 0.67 | EGFR (0.71) | NPSR1MEN1KMT2AHSP90AA1TLR9 | |
| SCHEMBL27955196 | 0.67 | EGFR (0.71) | NPSR1MEN1KMT2AHSP90AA1TLR9 | |
| SCHEMBL3594537 | 0.63 | PKM (0.63) | MEN1KMT2AHSP90AA1TLR9PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107827820-A | Pyrazolines aminopeptidase N inhibitor and its preparation method and application | 山东大学 | 2018-03-23 | — | — | CN | claimed |
| CN-107827820-A | Pyrazolines aminopeptidase N inhibitor and its preparation method and application | 山东大学 | 2018-03-23 | — | — | CN | disclosed |