Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.74 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | MAOB | P27338 | 8/20 | 0.66 |
| ▸ | MAOA | P21397 | 7/20 | 0.66 |
| ▸ | CA1 | P00915 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.63 |
| ▸ | PKM | P14618 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14138688 | 0.87 | PKM (0.79) | PKM | |
| SCHEMBL10016510 | 0.82 | POLB (1.00) | NPSR1POLBMAOBMAOACA1 | |
| SCHEMBL28343220 | 0.77 | MAOB (0.59) | POLBMAOBMAOACA1CA2 | |
| SCHEMBL28346042 | 0.77 | MAOB (0.52) | NPSR1POLBMAOBMAOACA1 | |
| SCHEMBL28205856 | 0.77 | MEN1 (0.74) | MAOBMAOAMEN1KMT2A | |
| SCHEMBL27918012 | 0.75 | MAOB (0.64) | NPSR1POLBMAOBMAOAKDM4E | |
| SCHEMBL7039863 | 0.74 | MEN1 (0.61) | NPSR1POLBMAOBMAOACA1 | |
| SCHEMBL28205907 | 0.73 | NPSR1 (0.56) | NPSR1POLBMAOBMAOACA1 | |
| SCHEMBL28810693 | 0.73 | L3MBTL1 (0.79) | NPSR1CA1CA2KDM4EMEN1 | |
| SCHEMBL14134000 | 0.72 | PKM (0.64) | NPSR1POLBMAOBMAOACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107827820-B | Pyrazoline aminopeptidase N inhibitor and preparation method and application thereof | 山东大学 | 2020-01-07 | — | — | CN | claimed |
| CN-107827820-A | Pyrazolines aminopeptidase N inhibitor and its preparation method and application | 山东大学 | 2018-03-23 | — | — | CN | claimed |
| CN-107827820-B | Pyrazoline aminopeptidase N inhibitor and preparation method and application thereof | 山东大学 | 2020-01-07 | — | — | CN | disclosed |
| CN-107827820-A | Pyrazolines aminopeptidase N inhibitor and its preparation method and application | 山东大学 | 2018-03-23 | — | — | CN | disclosed |