Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | ATM | Q13315 | 2/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.60 |
| ▸ | MAOA | P21397 | 4/20 | 0.54 |
| ▸ | MAOB | P27338 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | AOC1 | P19801 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28205313 | 0.80 | MEN1 (0.64) | MEN1KMT2AATMHSP90AA1MAOA | |
| SCHEMBL28205907 | 0.78 | NPSR1 (0.56) | MEN1KMT2AHSP90AA1MAOAMAOB | |
| SCHEMBL11713041 | 0.75 | MEN1 (0.69) | MEN1KMT2AATMHSP90AA1MAOA | |
| SCHEMBL28205856 | 0.74 | MEN1 (0.74) | MEN1KMT2AATMHSP90AA1MAOA | |
| SCHEMBL6292699 | 0.69 | ESD (0.75) | MEN1KMT2AATMHSP90AA1MAOA | |
| SCHEMBL27276997 | 0.67 | MAOB (0.76) | MEN1KMT2AMAOAMAOBAOC1 | |
| SCHEMBL6294304 | 0.65 | MEN1 (0.64) | MEN1KMT2AATMHSP90AA1MAOA | |
| SCHEMBL27277023 | 0.64 | MAOA (0.78) | MEN1KMT2AMAOAMAOBAOC1 | |
| SCHEMBL16740593 | 0.63 | PRKCZ (1.00) | MEN1KMT2AATMHSP90AA1MAOA | |
| SCHEMBL11064855 | 0.61 | MEN1 (0.54) | MEN1KMT2AATMHSP90AA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107827820-A | Pyrazolines aminopeptidase N inhibitor and its preparation method and application | 山东大学 | 2018-03-23 | — | — | CN | claimed |
| CN-107827820-A | Pyrazolines aminopeptidase N inhibitor and its preparation method and application | 山东大学 | 2018-03-23 | — | — | CN | disclosed |