Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.58 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 5/20 | 0.54 |
| ▸ | CA2 | P00918 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3310683 | 0.91 | LMNA (0.64) | CYP4A11LMNAHPGDCYP4F2LOXL2 | |
| SCHEMBL4928792 | 0.90 | CYP4A11 (0.66) | CYP4A11LMNAHPGDCYP4F2LOXL2 | |
| SCHEMBL24140330 | 0.89 | CYP4A11 (0.67) | CYP4A11LMNAHPGDCYP4F2LOXL2 | |
| Hydrochloric Acid SCHEMBL28375976 | 0.89 | CYP4A11 (0.64) | CYP4A11LMNAHPGDCYP4F2LOXL2 | |
| SCHEMBL9016956 | 0.87 | LMNA (0.68) | CYP4A11LMNAHPGDCYP4F2LOXL2 | |
| SCHEMBL13378249 | 0.86 | LMNA (0.59) | CYP4A11LMNAHPGDCYP4F2LOXL2 | |
| Hydrochloric Acid SCHEMBL15393160 | 0.85 | LMNA (0.66) | CYP4A11LMNAHPGDCYP4F2LOXL2 | |
| SCHEMBL7249257 | 0.85 | LOXL2 (0.64) | CYP4A11LMNAHPGDCYP4F2LOXL2 | |
| SCHEMBL15270773 | 0.85 | LMNA (0.57) | CYP4A11LMNAHPGDCYP4F2LOXL2 | |
| Hydrochloric Acid SCHEMBL16507466 | 0.85 | LMNA (0.57) | CYP4A11LMNAHPGDCYP4F2LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107873023-A | 3-alkyl-4-amido-bicyclo [4, 5, 0] hydroxamic acids as HDAC inhibitors | 福马治疗股份有限公司 | 2018-04-03 | — | — | CN | disclosed |