SCHEMBL28210206

SCHEMBL28210206

CCc1ccccc1N(N)c1ccccc1CN

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PNMT P11086 2/20 0.39
MGLL Q99685 1/20 0.37
CSNK2A2 P19784 1/20 0.37
CSNK2B P67870 1/20 0.37
CSNK2A1 P68400 1/20 0.37
CSNK2A3 Q8NEV1 1/20 0.37
DPP4 P27487 2/20 0.36
GABRA1 P14867 2/20 0.35
GABRB2 P47870 2/20 0.35
LOXL2 Q9Y4K0 3/20 0.33
LMNA P02545 1/20 0.33
ALDH1A1 P00352 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
TAAR1 Q96RJ0 1/20 0.32
AOC3 Q16853 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28210760 0.80 TP53 (0.38) PNMTCSNK2A2CSNK2BCSNK2A1CSNK2A3
SCHEMBL28858482 0.80 CSNK2A2 (0.42) MGLLCSNK2A2CSNK2BCSNK2A1CSNK2A3
SCHEMBL28210204 0.79 GABRA1 (0.41) PNMTDPP4GABRA1GABRB2LOXL2
SCHEMBL28210211 0.78 GABRA1 (0.34) PNMTDPP4GABRA1GABRB2LOXL2
SCHEMBL9799220 0.77 PTPN1 (0.47) ALDH1A1GAAMAPT
SCHEMBL79982 0.75 PNMT (0.50) PNMTMGLLCSNK2A2CSNK2BCSNK2A1
SCHEMBL9221189 0.75 MGLL (0.39) MGLLCSNK2A2CSNK2BCSNK2A1CSNK2A3
SCHEMBL22434077 0.75 MGLL (0.39) MGLLCSNK2A2CSNK2BCSNK2A1CSNK2A3
SCHEMBL14758687 0.75 AR (0.43) PNMTDPP4LOXL2ALDH1A1GAA
SCHEMBL8527904 0.74 TSPO (0.37) MGLLGABRA1GABRB2LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105985464-B Solid catalytic component for olefin polymerization and catalyst thereof 中国石油天然气股份有限公司 2018-04-03 CN disclosed