SCHEMBL28858482

SCHEMBL28858482

CCc1ccccc1N(N)c1ccc(CN)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 1/20 0.42
CSNK2B P67870 1/20 0.42
CSNK2A1 P68400 1/20 0.42
CSNK2A3 Q8NEV1 1/20 0.42
LOXL2 Q9Y4K0 5/20 0.38
TAAR1 Q96RJ0 1/20 0.37
PSIP1 O75475 1/20 0.37
GABRA1 P14867 2/20 0.34
GABRB2 P47870 2/20 0.34
MAOB P27338 2/20 0.34
HRH3 Q9Y5N1 1/20 0.33
MGLL Q99685 1/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28210760 0.87 TP53 (0.38) CSNK2A2CSNK2BCSNK2A1CSNK2A3TAAR1
SCHEMBL28210206 0.80 PNMT (0.39) CSNK2A2CSNK2BCSNK2A1CSNK2A3LOXL2
SCHEMBL28210267 0.76 TAAR1 (0.46) LOXL2TAAR1PSIP1HRH3CA2
SCHEMBL8527904 0.75 TSPO (0.37) GABRA1GABRB2MGLL
SCHEMBL28858410 0.73 LOXL2 (0.42) CSNK2A2CSNK2BCSNK2A1CSNK2A3LOXL2
SCHEMBL28210774 0.72 TLR8 (0.41) CSNK2A2CSNK2BCSNK2A1CSNK2A3LOXL2
SCHEMBL9221189 0.69 MGLL (0.39) CSNK2A2CSNK2BCSNK2A1CSNK2A3GABRA1
SCHEMBL22434077 0.69 MGLL (0.39) CSNK2A2CSNK2BCSNK2A1CSNK2A3GABRA1
SCHEMBL22400162 0.68 CSNK2A1 (0.58) CSNK2A2CSNK2BCSNK2A1CSNK2A3LOXL2
SCHEMBL439840 0.68 LOXL2 (0.59) CSNK2A1LOXL2TAAR1PSIP1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105985464-B Solid catalytic component for olefin polymerization and catalyst thereof 中国石油天然气股份有限公司 2018-04-03 CN disclosed