SCHEMBL28210372

SCHEMBL28210372

CC(=O)Oc1cc(N=O)ccc1N

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.39
TSHR P16473 3/20 0.39
ALDH1A1 P00352 2/20 0.39
GAA P10253 1/20 0.39
RAB9A P51151 1/20 0.39
CFD P00746 2/20 0.38
NR3C1 P04150 1/20 0.36
PTGS2 P35354 3/20 0.36
TNFSF11 O14788 1/20 0.36
LMNA P02545 1/20 0.36
ESR1 P03372 1/20 0.36
ITGB3 P05106 1/20 0.36
ITGA2B P08514 1/20 0.36
HMGB1 P09429 1/20 0.36
HPGD P15428 1/20 0.36
GGT1 P19440 1/20 0.36
PTGS1 P23219 1/20 0.36
BLM P54132 1/20 0.36
NAPRT Q6XQN6 1/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28210948 0.81 PIM1 (0.44) KDM4ETSHRALDH1A1GAARAB9A
SCHEMBL8681017 0.78 ALDH1A1 (0.55) KDM4ETSHRALDH1A1GAARAB9A
SCHEMBL26944947 0.78 ALDH1A1 (0.46) KDM4ETSHRALDH1A1GAARAB9A
SCHEMBL7065017 0.78 ALDH1A1 (0.55) TSHRALDH1A1GAAPTGS2LMNA
SCHEMBL31268447 0.77 LMNA (0.52) KDM4ETSHRALDH1A1GAARAB9A
SCHEMBL28382964 0.77 KDM4E (0.61) KDM4EALDH1A1GAARAB9ALMNA
SCHEMBL31268445 0.77 CYP3A4 (0.47) KDM4ETSHRALDH1A1GAARAB9A
SCHEMBL17423673 0.75 CFD (0.47) KDM4ETSHRALDH1A1GAARAB9A
SCHEMBL9050066 0.75 ABCB11 (0.50) KDM4ETSHRALDH1A1GAARAB9A
Acetamide SCHEMBL5081796 0.75 ALDH1A1 (0.52) KDM4ETSHRALDH1A1GAARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107892656-A A kind of preparation method of 2,5 diamino benzene ethanol 苏州盖德精细材料有限公司 2018-04-10 CN claimed
CN-107892656-A A kind of preparation method of 2,5 diamino benzene ethanol 苏州盖德精细材料有限公司 2018-04-10 CN disclosed